Martin L. Basch, Ph.D.

  • Assistant Professor
  • Otolaryngology - Head and Neck Surgery
  • Case Western Reserve University School of Medicine

 

 

 

GRADUATE MEDICAL EDUCATION
PhD

Developmental Biology, PhD - California Institute of Technology (2004)

Postdoctoral Training
House Ear Institute, Drs. Segil and Groves Labs - Inner Ear Development (2005-2009)

Baylor College of Medicine, Dr. Groves’ Lab - Inner Ear Development (2009-2015)

Dr. Basch, a native of Buenos Aires, Argentina, received his degree of  Licenciado en Ciencias Biológicas from the School of Sciences at the University of Buenos Aires. He earned his doctorate in 2004 working on Early Neural Crest Specification, Induction and Competence in Dr. Marianne Bronner’s lab at the California Institute of Technology. He started his postdoctoral training in the laboratories of Dr. Neil Segil and Dr. Andrew Groves at House Ear Institute in Los Angeles, and later become an instructor in Dr. Groves’ lab at Baylor College of Medicine. Dr. Basch joined the department of Otolaryngoloy at CWRU School of Medicine in May 2015.

RESEARCH INTERESTS
Stria Vascularis, Age-Related Hearing Loss, Organ of Corti Regeneration, Inner Ear Development

 

SELECTED PUBLICATIONS

1. Basch ML, Brown RM, Jen H and Groves AK., Where hearing starts: The development of the
mammalian cochlea., Journal of Anatomy, 2015, doi: 10.1111/joa.12314

2. Maass JC, Gu R, Basch ML, Waldhaus J, Lopez EM, Xia A, Oghalai JS, Heller S and Groves AK. Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea. Front Cell Neurosci. 2015 Mar 31;9:110

3. Moayedi Y, Basch ML, Pachecho NL, Gao S, Harrison S, Xiao N, Oghalai J, Overbeek PA, Mardon G and Groves AK; The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs., Plos Genetics, 2014 Jan;10 (1)e100455.

4.Basch ML, Ohyama T, Segil N, Groves AK; Canonical Notch signaling is not necessary for
prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa., J
Neurosci. 2011 Jun 1;31(22):8046-58

5. Ohyama T, Basch ML, Mishina Y, Lyons KM, Segil N, Groves AK; BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea., J Neurosci. 2010 Nov 10; 30(45):15044-51

Dr. Basch's PubMed Listing