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Amy Hise

Amy Hise

Amy Hise is a staff physician and researcher at the Louis Stokes Cleveland VA Medical Center and an Associate Professor of Pathology and International Health at Case Western Reserve University (CWRU). She earned a Masters Degree in Public Health from UCLA prior to earning her medical degree at the George Washington University Medical Center. After residency training in Internal Medicine at University Hospitals of Cleveland during which she carried out research on HIV and TB in Uganda and was awarded the Resident Research Award, she completed a research fellowship in Infectious Diseases at CWRU/UH, focusing on innate immune recognition of filarial parasites. She has studied the role of toll-like receptors (TLRs), C-type lectin-like receptors (CLRs), NACHT-domain containing or NOD-like receptors (NLRs) and RIG-like helicases (RLRs) in several infectious diseases, including lymphatic filariasis, onchocerciasis, mucosal candidiasis and Rift Valley fever virus. Her lab discovered a role for the NLRP3 inflammasome in host responses to mucosal candidiasis, as well as determining the innate PRR dependence of the IL-ß response to Candida. This work has been highly cited and formed the foundation of her current research studying the role of additional inflammasomes in anti-fungal host defense. She is an ad hoc reviewer for the NIH/Center for Scientific Review and serves as a peer-reviewer for multiple immunology and infectious diseases journals. Dr. Hise has extensive student and fellow mentoring experience and lectures in international health, virology and immunology. She received a Young Investigator Award from the American Society of Tropical Medicine & Hygiene and has been a finalist for two years for the Crain's Business Cleveland Health Care Hero Award, Advancements in Healthcare category. She was selected as a fellow in the FLEX Professional Development Program of WFSOM. Amy has served on the steering committee of WFSOM since 2003 and has held officer positions of Secretary and Vice President and President (current). During her free time Amy enjoys raising backyard chickens, organic gardening and spending time outdoors with her teenage son and multiple nieces and nephews.