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The Case Western Reserve University School of Medicine has contributed several historical breakthroughs in the fields of medicine and health. Indeed, the School boasts eight Nobel laureates among its faculty and alumni, including former professor of physiology John J.R. Macleod, who was awarded the Nobel Prize for Physiology and Medicine in 1923 for the discovery of insulin, and alumnus Paul C. Lauterbur, B.S. Chemistry '51, who shared the Nobel Prize for Physiology and Medicine in 2003 with Sir Peter Mansfield for discoveries in magnetic resonance imaging. Other notable research accomplishments by School faculty are the first surgical treatments of coronary artery disease, the first simulated milk formula for infants, development of the first heart-lung machine for use in open heart surgeries, the first successful genetic alteration of human cells in a test tube and creation of the first artificial human chromosome.
Today, research being conducted by faculty and students at the School ranges from the molecular basis of Alzheimer's disease and examining infectious diseases of the developing world to creating the first stool test that detects colon cancer, and much more. Of additional note, the School of Medicine was awarded $64 million from the National Institutes of Health/National Center for Research Resources to form the Clinical and Translational Science Collaborative in partnership with three hospital affiliates.
The Case Western Reserve University School of Medicine is affiliated with some of the best hospitals in the United States and is committed to developing a research portfolio that is aligned with their strategic clinical initiatives. School affiliates include University Hospitals Case Medical Center, Cleveland Clinic, The MetroHealth System and Louis Stokes Cleveland Department of Veterans Affairs Medical Center.
Through these partnerships, several cutting-edge technologies and research facilities are available to faculty and students. Core facilities of the School are the Case Medical Center, which comprises Case Western Reserve University and University Hospitals Health System, the Cleveland Clinic Lerner Research Institute, and the MetroHealth Medical System Rammelkamp Center for Education and Research. Additional prominent facilities include the Case Center for Imaging Research, Case Comprehensive Cancer Center, Center for Aids Research, National Prion Disease Pathology Surveillance Center (the only one of its kind in the United States), Center for Proteomics and Bioinformatics, and Center for Global Health and Disease.
To maintain such a high standard of biomedical research, the School of Medicine continually looks to the future. Upcoming objectives include developing a program in population health and personalized medicine, creating a Center for Membrane Biology, forming a Sleep Research Center and Sleep and Circadian Research Program, establishing a Center for Translational Therapeutics and Chemical Biology, and enhancing the Systems Medicine Program.