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case western reserve university

CENTER FOR PROTEOMICS AND BIOINFORMATICS

 

Current Proteomics (PHRM 555)

Instructors:
Masaru Miyagi (Course Director), Jinsook Chang, Janna Kiselar, Anne Distler, Rob Ewing, Wuxian Shi, Mark Chance, Sayan Gupta

Class time and location:
Location: BRB932
Lecture: Wednesday 1-3 pm
Laboratory: Wednesday 1-4 pm
Journal presentation: Monday noon-1 pm

Course Description: This course is designed for graduate students across the university who wish to acquire a better understanding of fundamental concepts of proteomics and hands-on experience with techniques used in current proteomics. Lectures will cover protein/peptide separation techniques, protein mass spectrometry, bioinformatics tools, and biological applications which include quantitative proteomics, protein modification proteomics, interaction proteomics, structural genomics and structural proteomics. Laboratory portion will involve practice on the separation of proteins by two-dimensional gel electrophoresis, molecular weight measurement of proteins by mass spectrometry, peptide structural characterization by tandem mass spectrometry and protein identification using computational tools. The instructors' research topics will also be discussed.