Selected Core and Collaborative Publications

 

1999

 

Burley, S.K., Almo, S.C., Bonanno, J.B., Capel, M., Chance, M.R., Gaasterland, T., Lin, D., Sali, A., Studier, W., Swaminathan, S. Structural Genomics: Beyond the Human Genome Project. Nature Genetics 23: 151-157 (1999).

 

Chance, M.R. X-ray Absorption Studies of B12 Coenzymes. Chemistry & Biochemistry of B12 . Banerjee, R., Editor, J. Wiley, NY, p. 43-72 (1999).

 

Deo, R.C., Bonanno, J.B., Sonenberg, N., Burley, S.K. Recognition of Polyadenylate RNA by the Poly(A)-Binding Protein. Cell 98: 835-845 (1999).

 

Edwards, A.M., Zhang, K., Nordgren, C.E., Blasie, J.K. Polarized XAS on Vectorially-Oriented Single Monolayers of Cytochrome c. J. Synchrotron Rad. 6: 411-413 (1999).

 

Fedorov, A., Fedorov, E., Gertler, F., Almo, S., Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeleton dynamics and neural function. Nature Struct. Biol. 6: 661-665 (1999).

 

Hickman, A.B., Klein, D.C., Dyda, F. Melatonin Biosynthesis: the Structure of Serotonin N-Acetyltransferase at 2.5 A Resolution Suggests a Catalytic Mechanism. Mol. Cell 3: 23-32 (1999).

 

Huang, L., Kinnucan, E., Wang, G., Beaudenon, S., Howley, P.M., Huibregtse, J.M., Pavletich, N.P. Structure of an E6AP-UbcH7 Complex: insights into Ubiquitination by the E2-E3 Enzyme Cascade. Science 286: 1321-1326 (1999).

 

Hurley, J.H. Structure, Mechanism, and Regulation of Mammalian Adenylyl Cyclase. J. Biol. Chem. 12: 7599-7602 (1999).

 

Levin, S., Almo, S.C., Satur, B.H. Functional Diversity of the Phosphoglucomutase Superfamily: Structural Implications. Protein Eng. 9: 737-746 (1999).

 

Lubkowski, J., Dauter, Z., Yang, F., Alexandratos, J., Merkel, G., Skalka, A.M., Wlodawer, A. Atomic Resolution Structures of the Core Domain of Avian Sarcoma Virus Integrase and its D64N Mutant. Biochemistry 38: 13512-13522 (1999).

 

Lubkowski, J., Dauter, Z.B., Yang, F., Alexandratos, J., Merkel, G., Skalka, A.M., Wlodawer, A. Atomic Resolution Structures of the Core Domain of Avian Sarcoma Virus Integrase and its D64N Mutant. Biochemistry 38: 13512-13522 (1999).

 

Maleknia, S.M., Brenowitz, M., Chance, M.R. Millisecond Radiolytic Modification of Peptides by Synchrotron X-Rays Identified by Mass Spectrometry. Anal. Chem. 71: 3965-3973 (1999).

 

Maleknia, S.M., Chance, M.R., Downard, K. Electrospray-Assisted Modification of Proteins by Radicals. Rapid Comm. in Mass Spectrometry 13: 2352-2358 (1999).

 

Miller, L.M., Hamerman, D., Chance, M.R., Carlson, C.S. Analysis of Bone Protein and Mineral Composition in Bone Disease Using Synchrotron Infrared Microspectroscopy. SPIE 3775: 104-112 (1999).

 

Miller, L.M., Tague, T. Novel Combination of Fluorescence Microscopy with Infrared Micro-Spectroscopy. NSLS Activity Report 2-87-2-90 (1999).

 

Pavletich, N.P. Mechanisms of Cyclin-Dependent Kinase Regulation: Structures of Cdks, their Cyclin Activators, and Cip and INK4 Inhibitors. J. Mol. Biol. 5: 821-828 (1999).

 

Pinard, R., Lambert, D., Walter, N.G., Heckman, J.E., Major, F., Burke, J.M. Structural Basis for the Guanosine Requirement of the hairpin Ribozyme. Biochemistry 38: 16035-16039 (1999).

 

Porschke, D., Burke, J.M., Walter, N.G. Global Structure and Flexibility of Hairpin Ribozymes with Extended Terminal Helicies. J. Mol. Biol. 289: 799-813 (1999).

 

Ralston, C.Y., Brenowitz, M., Chance, M.R. Early Folding Intermediates and Kinetic Traps in RNA Folding Revealed by Synchrotron Hydroxyl-Radical Footprinting. NSLS Activity Report 2-25-2-26 (1999).

 

Rhee, S., Han, Z.J., Liu, K., Miles, H.T., Davies, D.R. Structure of a Triple Helical DNA with a Triplex-Duplex Junction. Biochemistry 38: 16810-16815 (1999).

 

Sazinksy, M.H., Ehrenfeld, J., Jaffe, E.K., Scarrow, R.C. Zinc Ligation in the Active Site of Human and Bovine Porphobilinogen Synthases. J. Inorg. Biochem. 74: 287 (1999).

 

Shi, W., Li, C.M., Tyler, P.C., Furneaux, R.H., Cahill, S,M., Girvin, M.E., Grubmeyer, C., Schramm, V.L., Almo, S.C. The 2.0 A Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor. Biochemistry 31: 9872-9880 (1999).

 

Shi, W., Schramm, V.L., Almo, S.C. Nucleoside Hydrolase from Leishmania Major. Cloning, Expression, Catalytic Properties, Transition State Inhibitors, and the 2.5-a Crystal Structure. J. Biol. Chem. 30: 21114-21120 (1999).

 

Stebbins, C.E., Kaelin, W.G.,Jr., Pavletich, N.P. Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function. Science 284: 455-461 (1999).

Wang, X., Ho, R.Y.N., Whiting, A.K., Que, L., Jr. Spectroscopic Characterization of a Ternary Phosphatase-Substrate-Fluoride Complex. Mechanistic Implications for Dinuclear Hydrolases. J. Am. Chem. Soc. 12l: 9235-9236 (1999).

 

Yang, Z.N., Mueser, T.C., Kaufman, J., Stahl, S.J., Wingfield, P.T., Hyde, C.C. The Crystal Structure of the SIV gp41 Ectodomain at 1.47 A Resolution. J. Struct. Biol. 126: 131-144 (1999).

 

ZuPutlitz, J., Yu, Q., Burke, J.M., Wands, J.R. Combinatorial Screening and Intracellular Antiviral Activity of Hairpin Ribozymes Directed Against Hepatitis B Virus. J. Virol. 73: 5381-5387 (1999).