Types of Aneurysms, Etiologies and Risk Factors
Any conditions which either compromise the integrity of the vasculature, increase pressure in vessels, or contribute to abnormal hemodynamic flow may contribute to aneurysm formation.
Furthermore, studies have found that cigarette smoking, female sex, and younger age have been shown to correlate with aneurysm growth and rupture2.
Conditions associated with high intravascular pressure1,2,5:
Heavy alcohol use
Coarctation of the aorta
Polycystic kidney disease
High flow AVMs
Conditions associated with compromised vascular integrity1,2,5:
Infective processes, particularly bacterial endocarditis
Conditions associated with abnormal hemodynamic flow1,2,5:
In addition, some studies have found that family history of aneurysms, even in the absence of genetic syndromes usually associated with aneurysms, confers a 2-7 fold increased risk of developing at least one aneurysm6.
So called Familial intracranial aneurysm syndrome is diagnosed when 2 or more third degree or closer relatives have been diagnosed with cerebral aneurysms1.