Connie Piccone, MD

Contact Information

11100 Euclid Ave, RBC 6054
Cleveland, OH 44106
Phone: 216-844-3345
Fax: 216-844-5431



Connie Piccone, MD

Assistant Professor

  • Division: Hematology / Oncology


Dr. Piccone developed a commitment to research well before her medical school training, acquiring valuable laboratory experience in the Department of Mathematical and Computational Biology at the National Cancer Institute, National Institutes of Health. As a summer laboratory intern awarded a Cancer Research Training Award, she was directly involved in experimentation concerning protein-carbohydrate interactions, specifically the structure-function relationship of glycosyltransferases. As a Pediatric Resident at Rainbow Babies and Children’s Hospital, she solidified her passion for hematology/oncology and continued to expand her research experience, completing a senior resident research project entitled “Resident Knowledge and Education in End of Life Care.” Specifically, this study focused on grief and bereavement experiences among pediatric residents and was her first interaction with the process of study submission through an IRB. During her hematology/oncology fellowship at The Children’s Hospital of Philadelphia (CHOP), she developed and completed research protocols to establish a solid foundation for collaborative clinical research. The first project involved a retrospective cohort study on the outcome of immunosuppressive therapy (IST) for pediatric patients with severe aplastic anemia (AA). The second project was a retrospective case-control study of pediatric patients with sickle cell disease and gallbladder pathology. Currently, she is an Assistant Professor of Pediatrics at Case Western Reserve University (CWRU) and an attending hematologist/oncologist at UH Rainbow Babies and Children’s Hospital (RB&C), a premier center for pediatric and hematologic research. She is also the Clinical Director of the Sickle Cell Anemia Center. In her current position, she is involved in numerous clinical research projects, including a multicenter, NIH-funded trial, the TWiTCH study, a collaborative study with Radiology and Nephrology assessing new MRI techniques in renal disease in sickle cell disease, and a Planning Grant through the AAP CATCH program to improve educational/vocational resources for patients with sickle cell disease.