Anesthesia, Analgesia and Tranquilization
The Case IACUC has adopted guidelines developed by
the National Institutes of Health (NIH) for preanesthesia,
anesthesia, analgesia, sedation, tranquilization, and
restraint of laboratory animal species. The guidelines
are linked for each species below. The entire document
is available as an Acrobat .pdf file for download.
Additional information on the use of drugs in lab animal
veterinary practice can be found at the University
of Minnesota's Veterinary Formulary.
Tables by Species
• Mouse
• Rat
• Hamster
• Guinea Pig
• Rabbit
• Cat
• Dog
• Sheep and Goat
• Swine
• Nonhuman Primates
• Amphibians
The dosage recommendations and other data presented
on these pages were based upon data in the literature
and the professional judgment of veterinarians on the
NIH Animal Care and Use Committee Subcommittee on Training.
Doses published in the literature are often variable.
Proper drug doses may vary greatly depending on species,
strain, sex, age, physiologic status of the animal,
and the level of anesthesia/analgesia desired.
Although these lists provide a ready source
of information on drug doses, individuals should
not use these drugs without prior experience or appropriate
training. The attending veterinarians are available
for consultation and additional information through
the Animal Resource Center at 368-3490.
Controlled drugs are identified by a "C." The Roman
numeral classifies the drug into one of the five established
schedules of controlled substances (e.g., sodium pentobarbital,
CII).
All ordering of controlled drugs such as buprenorphine
must be done through the Animal Resource Center because
the ARC holds the DEA license. A Powerpoint presentation
is available at http://labanimals.cwru.edu/training.htm for
the proper ordering directions.
Remaining drugs, including prescription drugs, may
be ordered through University Purchasing.
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