MMPC Analytical Core
Mouse Metabolic Phenotyping Center (MMPC)
Biomedical Research Institute (BRB), 9th Floor
Henri Brunengraber, MD, PhD, Center Director
Stephen Previs, PhD, Core Director
Henri Brunengraber, MD, PhD, Vernon Anderson and Xin Yu, Core Co-Directors
Contact:
Serves: US and international scientific community
Overview
Case Western Reserve University is one of six centers housed at academic institutions http://www.mmpc.org/. Specifically, CASE MMPC provides the scientific community, local and at-large, with standardized and sophisticated metabolic phenotyping services for mouse models of various metabolic disorders. CASE MMPC permits researchers to ship their mice and obtain, on a fee-for-service basis, a range of complex tests used to characterize mouse metabolism, blood composition including hormones, energy balance and physical activity, eating and exercise, insulin resistance, organ function, metabolic fluxes and morphology physiology, histology and measures of diabetic complications in heart, kidney, etc. Many of surgical and procedural tests are performed on living animals and are designed to solve subtle and complex traits that often define models of metabolic disease. The Analytical and Metabolomic Core analyzes tissues, blood, plasma and urine from experiments conducted at the MMPC or from the user’s lab under the direction of Dr. Stephen Previs. The Core conducts all assays involving the determination of isotope labeling and concentration profiles of numerous metabolites.
Page last updated: September, 2007
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