C Guidelines For
The CWRU IACUC has adopted guidelines developed by the National Institutes
of Health (NIH) for preanesthesia, anesthesia, analgesia, sedation,
tranquilization, and restraint of laboratory animal species. The guidelines
are linked for each species below. .
Additional information on the use of drugs in lab animal veterinary
practice can be found at the University of Minnesota's Veterinary
Formulary.
Tables by Species
The dosage recommendations and other data presented on these pages
were based upon data in the literature and the professional judgment
of veterinarians on the NIH Animal Care and Use Committee Subcommittee
on Training. Doses published in the literature are often variable.
Proper drug doses may vary greatly depending on species, strain,
sex, age, physiologic status of the animal, and the level of
anesthesia/analgesia desired.
Although these lists provide a ready source of information
on drug doses, individuals should not use these drugs without prior
experience or appropriate training. The Animal Resource Center veterinarians
are available for consultation and additional information at 368-3490.
Controlled drugs are identified by a "C." The Roman numeral classifies
the drug into one of the five established schedules of controlled
substances (e.g., sodium pentobarbital, CII).
All ordering of controlled drugs such as buprenorphine must be
done through the ARC because the ARC holds the DEA license. Remaining
drugs including prescription drugs may be ordered through University
Purchasing. Marcaine, for example, falls in this latter category.
The ARC has a process in place for ordering controlled drugs for
investigators. It is initiated by completing an ARC requisition
for the drug requested. When the controlled drug arrives, the ARC
contacts the PI and dispenses the drug along with a record sheet
to keep track of use (per Drug Enforcement Agency requirements).
In order to make a second order of the same drug, the PI must present
the record sheet along with the requisition. The DEA requires that
the controlled drugs must be stored in the PI's lab in a LOCKED
cabinet. The ARC keeps track of the expiration date for all drugs
disbursed and contacts the PI to return expired drugs. DEA accountability
requires that expired controlled drugs MUST be returned to the ARC
and may not be discarded in the trash or poured down the drain.
Abbreviations
IV |
intravenous |
IM |
intramuscular |
IP |
intraperitoneal |
SC |
subcutaneous |
PO |
per os, oral |
IH |
inhalation |
qXh |
every X hours |
|
