Physiologic parameters:
|
Body temperature
|
38-39.6° C
|
|
Heart rate
|
130-325/min
|
|
Respiratory rate
|
32-60/min
|
|
Tidal volume
|
4-6 ml/kg
|
Many rabbits have serum atropinesterase which
causes reduced response to atropine. Glycopyrrolate,
another anticholinergic, can be used instead
of atropine.
Unique hypnotism or immobilization reflex has
been observed in rabbits in the absence of drug
use.
Large cecum can act as reservoir for anesthetics.
Depending on drug solubility, the cecum can
alter the pharmacologic effect.
Induction of anesthesia using volatile anesthetics
(e.g., halothane and isoflurane) should be done
with caution due to initial breath holding when
animals are first exposed to irritating gas
vapors.
Give IV injections via marginal ear veins.
Restraint/Preanesthesia
| Indication and Drugs |
Dosage and Route
of Administration |
|
Ketamine
|
15-50 mg/kg
|
IM
|
|
Acetylpromazine
|
1.0-10 mg/kg
|
IM SC IV
|
|
Ketamine/Acetylpromazine (10:1)
|
15-50 mg/kg
|
IM
|
|
Diazepam, C-IV (Valium®)
|
5-10 mg/kg
|
IV IM
|
|
Glycopyrrolate
|
0.005-0.011 mg/kg
|
IM
|
Anesthesia
| Indication and Drugs |
Dosage and Route
of Administration |
|
Sodium Pentobarbital, C-II (3% solution
given slowly to effect)
|
15-40 mg/kg
|
IV
|
|
Thiamylal Sodium, C-III (Surital®, Bio-Tal®)
|
30-40 mg/kg
|
IV
|
|
Ketamine (Ketaset®, Vetalar®)
|
22-50 mg/kg
|
IM
|
|
Ketamine/Acetylpromazine:
|
|
|
|
Acetylpromazine
|
1.0-5.0 mg/kg
|
IM
|
|
Ketamine
|
20-44 mg/kg
|
IM
|
|
Ketamine/Xylazine:
|
|
|
|
Xylazine
|
5-10 mg/kg
|
IM
|
|
Ketamine
|
35-50 mg/kg
|
IM
|
|
Methoxyflurane (Metofane®)
|
To effect
|
IH
|
|
Halothane (Fluothane®)
|
To effect
|
IH
|
|
Isoflurane
|
To effect
|
IH
|
Analgesia
| Indication and Drugs |
Dosage and Route
of Administration |
|
Morphine, C-II
|
5 mg/kg q2-4h
|
SC IM
|
|
Meperidine, C-II (Demerol®)
|
2-10 mg/kg
|
IM IV SC
|
|
Pentazocine, C-IV (Talwin®)
|
10-20 mg/kg q4h
|
IM
|
|
Acetylsalicytic Acid (Aspirin)
|
500 mg/kg
|
PO
|
|
Buprenorphine
|
0.02-0.1 mg/kg q8-12h
|
SC
|
Reversal Agents
| Indication and Drugs |
Dosage and Route
of Administration |
|
Yohimbine
|
0.2 mg/kg
|
IV
|
