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Anesthesia and Analgesia for Swine (Sus
scrofa)
CWRU IACUC Guidelines For
Anesthesia, Analgesia and Tranquilization
Physiologic parameters:
|
Body temperature
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39° C
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Heart rate
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58-86/min
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Respiratory rate
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10-20/min
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Tidal volume
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420 ml
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Larger swine require a lower dose of many drugs in the given
ranges due to higher percent body fat.
Restraint/Preanesthesia
| Indication and Drugs |
Dosage and Route of Administration |
|
Atropine
|
0.04 mg/kg
|
IM
|
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Sodium Pentobarbital, C-II
|
8-11 mg/kg
|
IV
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Acetylpromazine
|
0.11-0.22 mg/kg
|
IM
|
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Xylazine (Rompun®)
|
2 mg/kg
|
IV
|
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Diazepam, C-IV (Valium®)
|
0.55-8.5 mg/kg
|
IV
|
Anesthesia
| Indication and Drugs |
Dosage and Route of Administration |
|
Sodium Pentobarbital, C-II
|
15-35 mg/kg
|
IV IP
|
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Sodium Thiopental, C-III (5%)
|
5-10 mg/kg
|
IV
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Thiamylal Sodium, C-III (4%) (Surital®, Bio-Tal®)
|
6-16 mg/kg
|
IV
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Ketamine (Ketaset®, Vetalar®)
|
15-20 mg/kg
|
IM
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Xylazine/Ketamine:
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Xylazine
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2 mg/kg
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IV
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Ketamine
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20 mg/kg
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IM
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Acetylpromazine/Ketamine:
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|
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Acetylpromazine
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0.44 mg/kg
|
IM
|
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Ketamine
|
22 mg/kg
|
IM
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Halothane (Fluothane®)
|
To effect
|
IH
|
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Halothane/Nitrous Oxide (50% O2 + 50% N20)
|
To effect
|
IH
|
Analgesia
| Indication and Drugs |
Dosage and Route of Administration |
|
Phenylbutazone
|
4-8 mg/kg q24h
|
PO
|
|
Acetylsalicytic Acid (Aspirin)
|
10-20 mg/kg q8h
|
PO
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Morphine, C-II
|
0.2-0.9 mg/kg
|
IM
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Meperidine, C-II (Demerol®)
|
4 mg/kg
|
IM
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Buprenorphine
|
0.005-0.01 mg/kg q8-12h
|
IM
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