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Anesthesia and Analgesia for Hamsters (Mesocricetus auratus)

CWRU IACUC Guidelines For
Anesthesia, Analgesia and Tranquilization

Physiologic parameters:

Body temperature

37-38° C

Heart rate

250-500/min

Respiratory rate

35-135/min

Tidal volume

0.6-1.4 ml

Syrian or golden hamster is very resistant to morphine - no sedation or hypnotic effects.

Syrian or golden hamster has an increased tolerance to pentobarbital.

Restraint/Preanesthesia

Indication and Drugs Dosage and Route of Administration

Atropine

0.01 mg/100 g

IP IM SC

Ketamine (10 mg/ml)

2.2-4.4 mg/100 g

IM

Ketamine/Acetylpromazine (10:1)

(dose based on ketamine)

2.2-4.4 mg/100 g

IM

Chlorpromazine

0.05 mg/100 g

IM

Anesthesia

Indication and Drugs Dosage and Route of Administration

Sodium Pentobarbital, C-II

3-9 mg/100 g

IP

Ketamine or Ketamine/Acetylpromazine: 10:1 (dose based on ketamine)

4-15 mg/100 g

IM

10-20 mg/ 100 g

IP

Ketamine/Xylazine:

   

      Xylazine

1.0 mg/100 g

IP IM

      Ketamine

10.0 mg/100 g

IP

Telazol®

2-8 mg/100 g

IP IM

Methoxyflurane (Metofane®)

To effect

IH

Halothane (Fluothane®)

To effect

IH

Isoflurane

To effect

IH

Carbon dioxide

To effect

IH

Analgesia

Indication and Drugs Dosage and Route of Administration

Meperidine (Demerol®)

0.2 mg/100 g

IM

Pentazocine (Talwin®)

0.2-0.3 mg/100 g

IM


                  

 

 
 


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