Andrew E. Sloan, M.D.
Director, Brain Tumor and Neuro-Oncology Center
Associate Professor of Neurological Surgery
Case School of Medicine
University Hospitals Case Medical Center
Medical School:
| Harvard Medical School Boston, MA |
M.D. | 1990 |
Graduate Medical Education:
| UCLA School of Medicine Los Angeles, CA |
General Surgery | 1990 - 1991 |
| UCLA School of Medicine Los Angeles, CA |
Neurological Surgery | 1991 - 1997 |
| MD Anderson Cancer Center Houston, TX |
Fellow, Neurosurgical Oncology | 1997 - 1998 |
Clinical Interests:
Brain Tumors, Convection Enhanced Delivery (CED), Gamma Knife and Cyberknife Stereotactic Radiosurgery, Image Guided Neurosurgery, Neurosurgery, Skull Base Surgery, Stereotactic Surgery, Tumor Vaccines (Immunotherapy)
Selected Publications (past five years):
Parajuli P, Mathupala S, Sloan AE. Systematic comparison of dendritic cell-based immunotherapeutic strategies for malignant gliomas: in vitro induction of cytolytic and natural killer-like T cells. Neurosurgery. 2004 Nov;55(5):1194-204.
Mathupala SP, Parajuli P, Sloan AE. Silencing of monocarboxylate transporters via small interfering ribonucleic acid inhibits glycolysis and induces cell death in malignant glioma: an in vitro study. Neurosurgery. 2004 Dec;55(6):1410-9; discussion 1419.
Barnholtz-Sloan JS, Severson RK, Stanton B, Hamre M, Sloan AE. Pediatric brain tumors in non-Hispanics, Hispanics, African Americans and Asians: differences in survival after diagnosis. Cancer Causes Control. 2005 Jun;16(5):587-92.
Lo SS, Chang EL, Sloan AE. Role of stereotactic radiosurgery and fractionated stereotactic radiotherapy in the management of intracranial ependymoma. Expert Rev Neurother. 2006 Apr;6(4):501-7.
Sehgal V, Delproposto Z, Haddar D, Haacke EM, Sloan AE, Zamorano LJ, Barger G, Hu J, Xu Y, Prabhakaran KP, Elangovan IR, Neelavalli J, Reichenbach JR. Susceptibility-weighted imaging to visualize blood products and improve tumor contrast in the study of brain masses. J Magn Reson Imaging. 2006 Jul;24(1):41-51.
Colen CB, Seraji-Bozorgzad N, Marples B, Galloway MP, Sloan AE, Mathupala SP. Metabolic remodeling of malignant gliomas for enhanced sensitization during radiotherapy: an in vitro study. Neurosurgery. 2006 Dec;59(6):1313-23; discussion 1323-4.
Mathupala SP, Guthikonda M, Sloan AE. RNAi based approaches to the treatment of malignant glioma. Technol Cancer Res Treat. 2006 Jun;5(3):261-9.
Lo SS, Chang EL, Yamada Y, Sloan AE, Suh JH, Mendel E. Stereotactic radiosurgery and radiation therapy for spinal tumors. Expert Rev Neurother. 2007 Jan;7(1):85-93.
Barnett GH, Linskey ME, Adler JR, Cozzens JW, Friedman WA, Heilbrun MP, Lunsford LD, Schulder M, Sloan AE. Stereotactic radiosurgery--an organized neurosurgery-sanctioned definition. J Neurosurg. 2007 Jan;106(1):1-5.
Barami K, Grow A, Brem S, Dagnew E, Sloan AE. Vascular complications after radiosurgery for meningiomas. Neurosurg Focus. 2007 Mar 15;22(3):E9.
Mathupala SP, Colen CB, Parajuli P, Sloan AE. Lactate and malignant tumors: a therapeutic target at the end stage of glycolysis. J Bioenerg Biomembr. 2007 Feb;39(1):73-7.
Chamberlain MC, Glantz MJ, Chalmers L, Van Horn A, Sloan AE. Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma. J Neurooncol. 2007 Mar;82(1):81-3.
Parajuli P, Mathupala S, Mittal S, Sloan AE. Dendritic cell-based active specific immunotherapy for malignant glioma. Expert Opin Biol Ther. 2007 Apr;7(4):439-48.
Beaumont TL, Kupsky WJ, Barger GR, Sloan AE. Gliosarcoma with multiple extracranial metastases: case report and review of the literature. J Neurooncol. 2007 May;83(1):39-46. Epub 2006 Dec 14.
Mathupala SP, Mittal S, Guthikonda M, Sloan AE. MicroRNA and brain tumors: a cause and a cure? DNA Cell Biol. 2007 May;26(5):301-10.
Barnholtz-Sloan JS, Maldonado JL, Williams VL, Curry WT, Rodkey EA, Barker FG 2nd, Sloan AE. Racial/ethnic differences in survival among elderly patients with a primary glioblastoma. J Neurooncol. 2007 Nov;85(2):171-80. Epub 2007 May 26.
Youssef AS, Guiot B, Black K, Sloan AE. Modifications of the transoral approach to the craniovertebral junction: anatomic study and clinical correlations. Neurosurgery. 2008 Mar;62(3 Suppl 1):145-54; discussion 154-5.
Barnholtz-Sloan JS, Williams VL, Maldonado JL, Shahani D, Stockwell HG, Chamberlain M, Sloan AE. Patterns of care and outcomes among elderly individuals with primary malignant astrocytoma. J Neurosurg. 2008 Apr;108(4):642-8.
Barnholtz-Sloan J, Sloan AE, Land S, Kupsky W, Monteiro AN. Somatic alterations in brain tumors. Oncol Rep. 2008 Jul;20(1):203-10.
Barami K, Sloan AE, Rojiani A, Schell MJ, Staller A, Brem S. Relationship of gliomas to the ventricular walls. J Clin Neurosci. 2009 Feb;16(2):195-201. Epub 2008 Dec 18.
Burgoyne AM, Palomo JM, Phillips-Mason PJ, Burden-Gulley SM, Major DL, Zaremba A, Robinson S, Sloan AE, Vogelbaum MA, Miller RH, Brady-Kalnay SM. PTPmu suppresses glioma cell migration and dispersal. Neuro Oncol. 2009 Mar 20.
Selected Chapters/Textbooks:
Sloan AE. Diagnosis and treatment of malignant gliomas. In Principles of Neurosurgery, Rengachary S and Ellenbogin R (eds). London, England:Mosby Publishers, Inc. 2004, pp. 451-468.
Grolleau A, Sloan AE, Mule J. Dendritic cell vaccines for cancer therapy. In Tumor Immunology and Cancer Vaccines, Khleif S (ed). New York, NY: Kluwer Academic Publishers, 2007, in press.
Sloan AE. Stereotactic resection of malignant brain tumors. In Neurosurgery Operative Color Atlas, 2nd Edition, Rengachary S and Ellenbogin R (eds). New York, NY: Thieme, 2007, pp 114-123.
Barger G, Sloan AE, Kupsky W. Medulloblastomas. In Textbook of Neuro-Oncology, M Berger and M Prados (eds). New York, NY: Kluwer Academic Publishers, 2004.
Zager JS, McLoughlin JM, Sloan AE, Sondak VK. Surgical management of melanoma. In Principles and Practice of Surgical Oncology, Silberman A and Silberman H (eds). New York, NY: Lippincott, Williams & Wilkins, 2007 (in press).
