LABORATORY OF NEUROGERIATRICS

 
 

Robert P. Friedland, MD

Robert P. Friedland, MDselect from the list to see details:
 
Education
Postgraduate Training
Professional Certification
Professional Activities
Community Advisory Activities
Extramural Advisory and Editorial Activities
Extramural and Intramural Research Support and Awards
Educational Activities
Membership in Professional Organizations
Committees
 

PUBLICATIONS

click here to access complete list of publications, abstracts and presentations

 

 

EDUCATION:

City College of New York, New York  
Degree:  B.S., Biology
1965-69
University of Kentucky College of Medicine 
Lexington, Kentucky
1969-71
Summer Fellowship in Neurology, Department of  Neurology
Boston University School of Medicine, Boston, MA
1970
Mount Sinai School of Medicine    
City University of New York, New York, NY
1971-73
M.D.
June 1973

top

POSTGRADUATE TRAINING:

Straight Medicine Internship 
Beth Israel Hospital, New York, New YorK
1973-74
Neurology Residency and Chief Residency
Mount Sinai School of Medicine, New York, New York
1974-77
Weatherhead School of Management, CWRU
 
Member, Professional Fellows Program (15 credits)
1992-1993
Banking & Finance 420: Health Finance & Economics (3 credits)
1993
Health Systems Management 456:  Issues in Health Management (3 credits)
1994

top

PROFESSIONAL CERTIFICATION:

Diplomate, National Board of Medical Examiners                          

1974

Certified, American Board of Psychiatry and Neurology                

1979

California, Physician and Surgeon (GO 39005)                               

1980-1995

California, Physician and Surgeon (GO 39005)

1986-91

Maryland, Physician and Surgeon (D33237)                                  

1988-91

District of Columbia, Medicine and Surgery (17144)                      

1988-91

Ohio, Doctor of Medicine (35-05-9810)                                         

1990-Present

top

PROFESSIONAL ACTIVITIES:

Research Fellow, National Institutes of Health
(Senile Dementia: Biological and Behavioral Aspects)
Albert Einstein College of Medicine, New York, New York
1977-78
Associate, Department of Neurology
Albert Einstein College of Medicine, New York, New York
Clinical Study of Aging, Dementia and Cerebral Blood Flow (133 Xe Inhalation)
1977-78
Assistant Attending Neurologist 
Lincoln Hospital, Bronx, New York
1977-78
Clinical Fellow       
Jacobi Hospital, Department of Neurology, Bronx, New York
1977-78
 
Assistant Professor of Neurology, in Residence
University of California, Davis
1978-85
Associate Professor of Neurology, in Residence
University of California, Davis
1985
Staff Neurologist     
Veterans Administration Medical Center, Martinez, California
1978-85
Assistant Chief, Neurology Service
Veterans Administration Medical Center, Martinez, California
1978-84
Attending Neurologist, Highland General Hospital
Oakland, California
1979-85
Guest Scientist, Donner Laboratory 
University of California, Berkeley
1979-85
Chief Neurologist      
Research Medicine Group Donner Laboratory
University of California, Berkeley
1982-85
Director and Founder, Northern California Alzheimer's
Disease Center, University of California Davis, Berkeley, California
1985
Chief, Brain Aging and Dementia Section 
Laboratory of Neurosciences, National Institute on Aging, NIH
1986-1990
Deputy Clinical Director
National Institute on Aging
1986-1990
Clinical Professor 
Department of Neurology
Georgetown University School of Medicine
1988-1990
Director, Alzheimer's Disease and Memory Disorders Clinic    
Georgetown University Hospital
1988-1990
Clinical Director
1990-1993
Acting Director
1993
Associate Director 
NIA Alzheimer's Disease Research Center
University Hospitals of Cleveland
1994
Associate Professor 
1990-2001
Professor   
Departments of Neurology, Psychiatry and Radiology
Case Western Reserve University School of Medicine
2001-present
Chief, Laboratory of Neurogeriatrics  
Department of Neurology
Case Western Reserve University School of Medicine
1994-Present

top

COMMUNITY ADVISORY ACTIVITIES:

Medical Advisor and Member, Board of Directors                        
Alzheimer’s Aid Society of Northern California

1983-85

Member, Scientific Advisory Committee
Family Survival Project, San Francisco

1984-1995

Chief Witness, California Assembly Select Committee                  
on Mental Health, Hearing on "Organic Brain Syndromes," State Capital, Sacramento

1984

Member, Ad Hoc Committee to Consider a National                     
Conference on Neurological Disease and Aging, Special Committee on Aging, U.S. Senate

1986

Consultant, WNET/Thirteen, New York

1988

Member, Neuroscience Advisory Panel, Conte Institute for Environmental Health, Pittsfield, MA

1993-1994

Consultant, Dementia and Driving Consensus Meeting, Swedish National Road Administration, Borlange

1994

           

top

EXTRAMURAL ADVISORY AND EDITORIAL ACTIVITIES:

Ad Hoc Reviewer of Research Programs

 

Research Service, VA Central Office

1984, 1986, 1988, 1989, 1991, 1993-95

Division of Research Grants, NIH

1987-1995, 1997, 1998

Human Frontier Science Program(EEC, Strasbourg)

1991, 1991-1993,1997

Edison Biotechnology Center

1992

Retirement Research Foundation

1993

Netherlands Organization for Scientific Research

1994

Alzheimer Association

1994, 1996-1999

British Columbia Health Research Foundation

1995, 1999

American Federation for Aging Research

1995-present

The National Institute for Psychobiology in Israel 

1998, 2002

Special Emphasis Panel, NIH, CSR

1998

Warrant Committee, Italian Ministry of Research

1998

Douglas French Foundation, Los Angeles

2002

top

 

Ad Hoc Referee of Submitted Manuscripts and Proposals

 

Agency for Health Care Policy and Research (DHHS)

1994

Annals of Neurology

1993-1995

Archives of Neurology

1986-1989, 1992,1997,2001-2004

Biological Psychiatry

1989-1991

Brain Research

1987, 1993

Investigative Radiology

1995

Journal of the American Geriatrics Society

1999

Journal of the American Medical Association

1991-1998,2000, 2002,2003

Journal of Cerebral Blood Flow and Metabolism

1987, 1988, 1992-1994

Journal of Computer Assisted Tomography

1987

Journal of Geriatric Psychiatry and Neurology

1991, 1996

Journal of Neuroimmunology

1999

Journal of Nuclear Medicine

1993-1996,1998,1999, 2002 

Lancet Neurology

Nature Biotechnology

Nature Medicine

2004

2001

2000

Neurobiology of Aging

1991-1993, 1999

Neuroepidemiology

2002

Neurology

1988-1997,2002

Neurology Network Commentary

1997

Proceedings of the National Academy of Sciences

Scanning Microscopy International

2001

1994

Science

1984, 1985

Seminars in Neurology

1998, 1999

top

 
Member, Alzheimer's Disease Review Panel Department of Health Services State of California
1985
Member, Editorial Board Alzheimer's Disease: an International Journal
1985-1994
Member, Scientific Program Committee, IX European 
International Neuropsychology Society Conference, Veldhoven
1986
Member, Scientific Program Committee (Neurology) Annual Meeting of the Society for Nuclear Medicine, Washington, D.C.
1986,1989
 
Office of Medical Applications of Research 
NIH Planning Committee:  Consensus Development Conference on Nuclear Magnetic Resonance Imaging
1986-87
Temporary Advisor, Division of Mental Health   
World Health Organization, Geneva, Switzerland
1987
Temporary Advisor, Division of Mental Health
World Health Organization, Beijing, China
1987
Consultant, World Health Organization Special Program for Research on Aging, Bethesda, MD.
1988
Consultant, "Cooperative Studies of Alzheimer's Disease in U.S. and Japan," National Institute of Neuroscience, National Center for Neurology and Psychiatry, Tokyo
1989
American Neurological Association, Representative
to the National Coalition for Research in Neurological Disorders
1991-1997
Consultant for Review of Drug Development
 
    Ayerst, Inc
1986
    Miles Pharmaceuticals 
1991
    Astra Zeneca
    Quintiles Pacific, Inc  
1999
2000
Consortium to Establish a Registry for Alzheimer's Disease (CERAD) (NIH) Clinical Task Force
1991-1996
Reviewer - Agency for Health Care Policy and Research (DHHS) Panel on recognition and initial assessment of Alzheimer's disease and related dementias
1994
Symposium Co-Organizer: "Neurodegenerative Disorders:  Common Molecular Mechanisms", Ocho Rios, Jamaica, Goteborg University and University of the British West Indies
March 1994
March 1995
March 1997
February 1998
Symposium Co-Organizer: "Neurodegenerative Disorders: Common Molecular Mechanisms," University of the British West Indies, Trinidad
April, 2000
Medical and Scientific Advisory Board                                                                                                  
Alzheimer's Association, Chicago (Ad hoc member)
1994
Symposium Co-Organizer: The Second Tel Aviv University Alzheimer's Disease Conference-Joint meeting with Case Western Reserve University (Supported by the Joseph & Florence Mandel Foundation, Cleveland, OH, Tel Aviv University, the NIA, and Philip Morris)($81,000)
May 1995
Consultant, Alzheimer’s disease and fitness for driving,                                                                         
Association for the Advancement of Automotive Medicine, National Highway Safety Administration, Sweden
1996
Consultant, Monitor/Tracker for Alzheimer’s disease, PI. R. Schmidt Cleveland Medical Devices Corporation NIH/SBIR
1996-1999
Member, American Federation for Aging Research,                                                                                
National Scientific Advisory Council
1996-present
Member, Review Board of the Medical and Scientific Advisory Council, Ronald and Nancy Reagan Research Institute, Alzheimer’s Association
1997-present
Member, Scientific Advisory Committee, National Institute for Psychobiology, Israel  
1999-present
Panel member, Workshop on Alzheimer’s Disease Epidemiology
Beethesda, NIH, National Institute on Aging
March, 1998
 
Consultant for Alzheimer’s disease drug studies and biomarkers
 
      Chrysalis Corporation, (Contract Research Organization)
      Austin, Texas
1997-1999
      Pfizer, Inc.
2000
Member, International Advisory Board, "Vascular Factors in Alzheimer’s Disease”,                                                                                                      
International Meeting, Northumberland, UK
May, 1999
Member, Special Emphasis Panel ZRG1 BDCN2(02)                                                                              
NIH Center for Scientific Review   
October, 1999
Member, Neuroscience of Aging Review committee, 
NIA Initial Review Group, NIH
June, 2000
Member, Scientific Review Board, Institute  
for the Study of Aging, New York
1999-present
Associate Editor and member, Editorial Board,                 
Journal of Alzheimer’s Disease
1999-2002
Principal Organizer, "First International Symposium on Alzheimer’s Disease in the Middle East”, Limassol, Cyprus
April, 2001
Reviewer, Human Frontiers Science Program, Strasbourg   
1999-2000
Member, Initial Review Board of the Medical and Scientific Advisory Council, Alzheimer’s Association
1999- present
Member, International Scientific Committee
Third World Congress on Vascular Factors in Alzheimer’s Disease
Kyoto
April, 2002
Principal Organizer, "First International Symposium on Alzheimer’s Disease in the Middle East”, Limassol
April, 2001
Principal Organizer, "Second International Symposium on Alzheimer’s Disease in the Middle East” Istanbul
 
External Reviewer, Michael Smith Foundation for Medical Research, Vancouver

  May, 2003

2001,
2002
Member, International Coordinating Committee, and Founding Member,  International Society for Vascular Behavioral and Cognitive Disorders (VAS-COG), First Meeting, Goteborg
August, 2003
Reviewer, State of Missouri Alzheimer’s Disease and Related Disorders Advisory Board
 
Member, Middle East Academy for Medicine of Ageing, Beirut
 
Member, Editorial Advisory Board, Current Alzheimer Research
 
 
Member, International Scientific Advisory Board, Alzheimer’s Disease International, Annual Meeting, Istanbul    
 
Principal Organizer, Third International Symposium on Alzheimer’s Disease in the Middle East, Istanbul
2003
 
  2003- present
 
 
2004-present 
 
 
October, 2005
 
 
October, 2005

                                           

top

EXTRAMURAL AND INTRAMURAL RESEARCH SUPPORT AND AWARDS:

           

Principal Investigator, "Effect of activation of ischemic neurons on recovery from stroke", University of California, Davis, Faculty Research Grant

 

1979-81

Principal Investigator, VA Merit Review Research Program, 

"Cerebral Metabolic Indices of Dementia Pathophysiology"

 

1981-84

Principal Investigator, (Renewal of above Program) "Structural and Functional Indices of Dementia Pathophysiology" ($47,337/year)

 

1984-85

Co-Investigator, "Ischemic Brain Disease," (NIH HL 25840), ($34,192/year), Principal Investigator, Philip Weinstein, M.D.

1983-85

Co-Investigator "Cerebral blood flow patterns in Alzheimer's disease", (NIH), ($187,000/year) Principal Investigator, Thomas F. Budinger, M.D., Ph.D.

1985

Principal Investigator, "Oxiracetam in the treatment of progressive degenerative dementia of mild to moderate severity", Ciba-Geigy Corporation ($67,000)

1985

Project Director and Founder "Northern California Alzheimer's Disease Center," Department of Health Services, State of California ($100,000/year)

1985

Chief, Brain Aging and Dementia Section 

National Institute on Aging, NIH  ($2.4 million/year) 

1986-1990

Director, Clinical Core

1990-1993

Acting Director

1993

Co-Director Clinical Core 

Alzheimer's Disease Research Center

University Hospitals of Cleveland NIA AG08012 ($1,386,582/year)

 

1994

Co-Investigator, Clinical Research Center for the Psychopathology of the Elderly NIMH MH43444 ($100,000/year)

 

1990-1991

Principal Investigator, Monoclonal antibodies for the immunochemical evaluation of Alzheimer's Disease

 - NIA ADRC Pilot grant ($22,150)

1990-1992

Co-Investigator, State of Ohio Center Grant "Causes and Treatments of Alzheimer's Disease" ($265,909/year)

1990-1992

Lawrence C. McHenry Award 

American Academy of Neurology

1990

Director Consortium to Establish a Registry for Alzheimer's

Disease Clinic (CERAD), Cleveland, NIA

1990-1996

Principal Investigator, "A Placebo Controlled Study of Acetyl-L-Carnitine in Patients with Alzheimer's Disease: A Multi-Center Study," Sigma-Tau Pharmaceuticals, Inc. ($140,000)

1991-1994

Principal Investigator (45%) “The effects of cigarette smoking on the development of Alzheimer's disease:  Epidemiological, Clinical and Neurobiological Studies."  Philip Morris USA

($6,989,078 Direct & Indirect Costs, 1991-1996)

1991-1996

Principal investigation (40%) "The effects of cigarette smoking  on the development of  Alzheimer’s disease: International epidemiological and neurobiological studies.” Philip Morris, USA,

(Jan. 1997-Dec.  2001) $9,809,202 (Direct and Indirect costs)                  

1997-2001

Principal Investigator (20%) “Monoclonal antibody imaging of cerebral A in Alzheimer’s disease,” Philip Morris USA ($59,103 Direct costs per year)

1991-1996

Sponsor, IND-BB-5059, "Technetium 99mTc Murine monoclonal antibody 10H3 Fab," Food and Drug Administration (Collaboration with the Massachusetts General Hospital, Mallinckrodt Medical and NeoRx Corporation) 

1994

Saul Horowitz, Jr. Memorial Award

Mt. Sinai School of Medicine, New York, New York

1994

Co-Investigator, "The effect of lazabemide on regional brain monoamine oxidase type B activity in patients with Alzheimer's Disease as measured by 11C-L-Selegiline positron emission tomography,"  Hoffmann-LaRoche, Inc.

1994-1995

Principal Investigator: “Cross-Cultural (Cleveland-Israel) studies of the basic and clinical sciences of Alzheimer's disease,” [(Joseph and Florence Mandel Foundation ($150,000)] 

1995-98

Principal Investigator: "A population based prevalence study of genetic and environmental factors for Alzheimer’s disease in Kenya”, Alzheimer’s Association (Chicago) - ($68,000 per year, direct and indirect costs)

1997-2000

Principal Investigator:  “Noninvasive imaging of cerebral amyloid- deposition in Alzheimer’s disease,” Nickman Family gift to University Hospitals of Cleveland ($250,000).        

1997-2003

Principal Investigator: CWRU Site, Multi-institutional Research on Alzheimer Genetic Epidemiology, NIA Grant (L. Farrer, PI)

1998-2008

Principal Investigator: Israel and Alzheimer’s disease, Epidemiology, Demography and Biometry Program, NIA, NIH, Contract #263-MO-818915, $22,950 (total costs)

1998-1999

Principal Investigator: "Genetic and environmental risk factors for Alzheimer’s disease in Israeli Arabs”, $50,000, Institute for the Study on Aging, New York, New York.

1999-2000

Principal Investigator: "Genetics of Alzheimer’s Disease in Israeli Arabs,” National Institute of Health, National Institute on Aging, NIH, $474,753 (total costs for year one) UO1 AG1713-01A1

     Renewal  resubmitted 11/03 ($5,807,317 total costs for           2003-2008)

NIH/NIA  Data Sharing Administrative supplement funded,      $77,1000 total costs, 9/1/03

 

2000-2003

Principal Investigator: "Genetic and environmental factors for Alzheimer’s disease in Israeli Arabs”, Institute for the Study of Aging, NY, (3 years, direct costs $210,000)

2000-2003

Principal Investigator, "First International Symposium on Alzheimer’s Disease in the Middle East” NIH R13 grant, (total costs $10,000) Institute for the Study of Aging, NY,  $30,000

2001-2002

Principal Investigator: "Family based studies of gene-environment

Interactions in Alzheimer’s disease” Philip Morris External Research Program, $2,111,035 total costs

2002-2005

 

Convener and primary organizer, Second International Symposium on Alzheimer’ s Disease in the Middle East, Istanbul, Turkey, May, 2003, National Institute on Aging (R13 AG021082-01A1), and  Alzheimer Association, USA ($89,000 direct costs).

2002 (pending)

 

Principal Investigator: “Labeling of cerebral ABeta deposits in vivo using intranasal administration of serum amyloid P component”

Presidential Technology Development Grant Program, CWRU

$50,000 direct costs

2002-2003

Principal Investigator, Unrestricted gift to CWRU for research support, $25,000, GOJO Corp., Akron, OH.

2003-2005

Principal Investigator, The First Congress of the International Society for Vascular Behavioral and Cognitive Disorders (Vas-Cog 2003) Goteborg, Sweden, August 28-31, 2003, NIH R13, $30,000 direct costs

2003-2004

Principal Investigator: Molecular epidemiology and neurobiology of anti-Abeta antibody-antigen interactions in Alzheimer’s disease”  Fullerton Family Foundation (Gift to CWRU), $300,000 direct costs

Principal Investigator, CWRU site, Multi-institutional Research in Alzheimer’s Genetic Epidemiology (MIRAGE) (L. Farrer, PI), $55,000/year direct costs, NIA, NIA

 

Principal investigator, Alzheimer’s disease African–American Education Program, Pfizer Corp., $43,000 total costs.

2002-2005

 

 2002-2007

 

 

2004-2005 

top

EDUCATIONAL ACTIVITIES:

Participation in Neurosciences Course       

University of California, Davis  (First and second year students)

 

1977-85

 

Instruction of medical students in Clinical Neurology

University of California, Davis

(Third and fourth year students)

 

1977-85

Supervisor of Neurology Residency Training Program   

University of California, Davis, Martinez VAMC Participation on Doctoral Qualifying Examination Committees, University of California, Berkeley

 

1977-82

Biophysics and Medical Physics

 

1981

Physiological Optics

1984

 

Instructor, Graduate Interdisciplinary Studies Course, IDS 271, "Seminars in Neuropsychology" (4), Department of Psychology, University of California, Berkeley

1981, 1982

Instructor, Graduate Interdisciplinary Studies Seminar on Memory Pathology, Department of Psychology, University of California, Berkeley

1983

Visiting Professor, Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky

1988

Course Coordinator, Neurobiology of Aging and Dementia, Clinical Elective for 3rd and 4th year medical students, Clinical Center, NIH

1985-1990

Course Coordinator, Type A Elective, Alzheimer's disease:  From biology to clinical medicine, CWRU School of Medicine

1992-present

Course Coordinator - Type A Elective -DGMS-2002 Critical Thinking for Clinical Medicine, CWRU School of Medicine

1995- present

Participation on Doctoral Qualifying Examination Committee, CWRU Department of Pathology 

1992-1995

Participating speaker, CWRU:

 

GEMD 3002: The Physiology of Aging

1994-present

Anthropology 215: Health Culture & Disease Introduction to Medical Anthropology

1996-present

Philosophy 101, Introduction to Philosophy

1999

Participant, CWRU School of Medicine Prematriculation Program

1997

Applicant Interviewer, CWRU School of Medicine 

1997-present

Member, Admissions Committee, CWRU School of Medicine

2000-present

Member, Dissertation Committee, Heather A. Lindstrom-Ufuti: "Determinants of Social Status in the Elderly. A field study in American and Western Samoa,” CWRU Department of Anthropology 

1999-present

Course Director:  "Alois Alzheimer and his Friends,” American Academy of Neurology Educational Program, Annual Meeting, Philadelphia

Member, Dissertation Committee, Abdalla Bowirrat, MD, Tel Aviv University, Dept. of Neurology, “Epidemiological and Genetic Studies of Alzheimer type Dementia in an Elderly Arab Population in Israel”

2000

 

2001

 

External Thesis Examiner, N. Cookson, University of Newcastle, Faculty of Medicine, MPh.

2002

Mentor, Independent Studies, CWRU graduate students in Epidemiology and  Biostatistics

2004

top

MEMBERSHIP IN PROFESSIONAL ORGANIZATIONS:

            American Neurological Association
 
            American Academy of Neurology, Fellow
                        Geriatric Neurology Section (Research Committee)
                        Behavioral Neurology Section
                        Section on Neuroepidemiology
 
International Society for Vascular Behavioural and Cognitive Disorders (VAS-COG)(Founding Member)
           
            Society for Neuroscience
 
            Behavioral Neurology Society
 
            World Federation of Neurology
                          Research Group on Neuroepidemiology
                          Dementia Research Group

COMMITTEES:

VA Medical Center, Martinez

 

Quality Assurance Committee

1978-85

Neurology Service Quality Assurance Committee (Chairman)

1984-85

Pharmacy and Therapeutics Committee

1979-82

Library Advisory Committee (Vice-Chairman)

1978-84

Research and Development Committee

1985

 

Lawrence Berkeley Laboratory

1980-85

University of California, Berkeley Pituitary Tumor Board 

 

           

University of California, Davis School of Medicine

1982-85

Admissions Committee

National Institutes of Health

 

Clinical Center Medical Board

Subcommittee on Promotions

1986-1990

 

PET Steering Committee (Secretary)

1987-1989

             

Case Western Reserve University/University Hospitals of Cleveland

 

ElderHealth Center Advisory Committee

1990-1994

Subcommittee on Neurology Resident Education

1991-Present

Department of Neurology, Credentials Committee

1991-Present

Committee on Appointments, Promotion and Tenure

1995-Present

Pharmacy and Therapeutics Committee

Center on Aging and Health,

1991-1992

       Senior Faculty Associate, member

       Development Committee

1991-Present

           1999-Present

CWRU/Henry Ford Hospital Affiliation Committee

1992-1994

Flexible Elective Committee

1995-Present

Neurology Coordinator, Generalist Initiative

1995-Present

           

Department of Neurology -Investigational Review Committee

 

(Chair)

1995-1996

Radiation Safety Committee

1996-Present

Radioactive Drug Research Committee

1996 -Present

Primary Care Track Committee

1996-Present

Admissions Committee (SOM)

2000-Present

top

   

CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE

 About Us      Work     Collaborators    Sponsors/Partners     Links   
  2004 Robert P. Friedland, MD