The
effects of nicotine on amyloid beta protein aggregation
(Principal investigator
Michael Zagorski, PhD, Department of Chemistry, CWRU)
We
have reported that nicotine inhibits the aggregation
of amyloid ß protein, enhancing itssolubility of
this important protein in vitro. Nicotine and
related compounds are
being studied for effect on amyloid ß aggregation.
This work may have important implications for the
development of anti-amyloid therapies.
