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Center for Aids Research

Center for Aids Research Mentors: Students Training in AIDS Research

Faculty Contact Info Research Focus
Jonathan Karn, Ph.D.
Reinberger Professor of Molecular Biology
Department of Molecular Biology and Microbiology
Assistant: Brinn Omabegho
Ph. 368-3915
HIV Eradication and Cure. Projects include: development of new methods to measure latent HIV reservoirs; engineering of NK cells to eliminate latently infected cells; development of new drug regimens to reactive the latent reservoir.
Ann Avery, M.D.
Associate Professor of Medicine
MetroHealth Medical Center
HIV retention in care, depression screening and treatment in HIV, PrEP rollout, HIV testing
W. Henry Boom, M.D.
Professor of Medicine
Director, Tuberculosis Research Unit
Epidemiology of MTB (TBRU with Charles Bark and/or Cathy Stein's help)
David Canaday, M.D.
Associate Professor of Medicine, Case Western Reserve University
Associate Director, Geriatric, Research, Education and Clinical Center (GRECC)
Louis Stokes Cleveland VA Medical Center
Ph. 368-8901
Human immunity to infectious diseases, understanding the mechanisms of increased pathogenesis during HIV/TB co-infection specifically involving properties of the interactions of T cells with macrophages and dendritic cells that foster loss of control of TB infection; defects in the human immune system that occur with aging
Amy Hise, M.D., MPH
Assistant Professor
Center for Global Health and Diseases
Innate immunology, inflammasomes, Rift Valley fever virus and fungal immunology
Christopher King, M.D., Ph.D.
Professor of International Health, Medicine and Pathology
Center for Global Health and Diseases
HIV effects on pregnancy from Kenya (data analysis with Indu Malhotra).
Alan Levine, Ph.D.
Department of Medicine
Division of Gastroenterology and Liver Disease.
Characterize the mucosal T cell and epithelial-mediated immune response in HIV patients both before and after effective and failed anti-retroviral therapy, and use this knowledge to design strategies that can stimulate host defenses in the gut to prevent an HIV infection in the first place
David McDonald, Ph.D.
Associate Professor
Department of Molecular Biology and Microbiology
Defining the mechanisms of HIV trafficking within dendritic cells with the long-term goal of understanding the complex interactions between pathogens and the cells they infect
Liem Nguyen, Ph.D.
Assistant Professor
Department of Molecular Biology and Microbiology
Antibiotic resistance and bacterial pathogenesis
Pushpa Pandiyan, Ph.D.
Assistant Professor
Department of Biological Sciences
Mechanisms of immune regulation. Ways to manipulate regulatory T cell and inflammatory Th17 cell development
Carlos Subauste, M.D.
Associate Professor of Medicine, Ophthalmology and Pathology
Host-pathogen interactions using Toxoplasma gondii, a major opportunistic pathogen in AIDS patients. In particular, we study: 1) The role of CD40 and autophagy in promoting protection against T. gondii and 2) The molecular mechanisms by which T. gondii alters signaling in host cells to avoid being killed by autophagy
John "Chip" Tilton, M.D.
Assistant Professor
Center for Proteomics and Systems Biology
Host and viral factors that regulate the susceptibility of primary immune cells to infection by HIV. Our research merges mutagenesis and molecular virology approaches with cellular immunology to identify critical host-viral protein interactions that can be blocked to reduce HIV transmission or promoted to improve retroviral-based gene therapy approaches
Saba Valadkhan, Ph.D.
Assistant Professor
Department of Biochemistry
Role of long non-coding RNAs in host response to viral infections, with special emphasis on HIV. Using a combination of computational and molecular biology approaches, we aim to understand the mechanism of regulation of host response pathways by non-coding RNAs
Lance Vernon, DMD, MPH
Senior Instructor
Department of Biological  Sciences
Periodontal disease and cardiovascular disease in HIV+ adults
Allison Webel, R.N., Ph.D.
Assistant Professor
Frances Payne Bolton School of Nursing
Clinical and behavioral research on HIV patients.
Tsan Sam Xiao, Ph.D.
Associate Professor
Division of Anatomic and Experimental Pathology
Department of Pathology
Role of the IFI16 inflammasome in the depletion of CD4 T cells upon HIV infection. The IFI16 inflammasome recognizes DNA derived from viral reverse transcripts and induces the activation of caspase-1 and pyroptotic cell death in CD4 T cells.
Wen-Quan Zou, M.D., Ph.D.
Associate Professor
Institute of Pathology
Investigate the role of cellular prion protein in the pathogenesis of neurodegenerative disorders including prion disease, Alzheimer's disease and HIV-associated neurocognitive disorder using cell/animal models and patients' samples