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Nicola Lai, Ph.D.

Education
  • 1998 (BS+MS) Chemical Engineering
    University of Cagliari - Dep. of Chemical Engineering and Materials, Cagliari, Italy.
  • 2002 Ph.D. Chemical Engineering
    University of PISA - Dep. of Chemical Engineering and Materials, Cagliari, Italy.
Research Interests
  • Mass transport and metabolism in cell, tissue & organ systems
  • Mathematical modelling & analysis of dynamic and distributed system
  • Systems Integrated Physiology
  • Tissue Engineering
Publications
  • Lai N, Zhou H, Saidel GM, Wolf M, McCully K, Gladden LB, Cabrera ME. Modeling oxygenation in venous blood and skeletal muscle in response to exercise using near-infrared spectroscopy. J Appl Physiol. 106(6):1858-74, 2009.
  • Zhou H, Lai N, Saidel GM, Cabrera ME. Multi-scale modeling of respiration: linking external to cellular respiration during exercise. IEEE Engineering in Medicine and Biology 28(3):34-40, 2009;
  • Lai N, Saidel GM, Iorio M, Cabrera ME. Non-invasive estimation of metabolic flux and blood in working muscle: effect of blood-tissue distribution. Adv Exp Med Biol. 645:155-60, 2009;
  • Lai N, Syed N, Saidel GM, Cabrera ME. Muscle oxygen uptake differs from consumption dynamics during transients in exercise. Adv Exp Med Biol. 614:325-32, 2008;
  • Zhou H, Lai N, Saidel GM, Cabrera ME. Multi-scale model of O2 transport and metabolism: response to exercise. Ann. N. Y. Acad. Sci., 1123(1): 178�186, 2008.
  • Lai N., Nasca M., Silva M.A., Silva F.T., Whipp B.J. and Cabrera M.E., Influence of exercise intensity on pulmonary oxygen uptake kinetics at the onset of exercise and recovery in male adolescents Appl. Physiol. Nutr. Metab. 33(1): 107-117 (2008).
  • Lai N., Saidel G.M., Grassi B., Gladden L.B., and Cabrera M.E. Model of O2 transport and metabolism predicts effect of hyperoxia on canine muscle oxygen uptake dynamics. J. Appl. Physiol. 103:1366-78, 2007.
  • Lai N., Camesasca M., Saidel G., Dash R.K., and Cabrera M.E., Linking pulmonary oxygen uptake, muscle oxygen utilization and cellular metabolism during exercise, Ann. of Biomed. Eng., 956-969, 2007.
  • Lai N., Dash R.K., Nasca M.M., Saidel G. and Cabrera M.E., Relating pulmonary oxygen uptake to muscle oxygen consumption at exercise onset: in vivo & in silico studies, European Journal Applied Physiology, 97: 380-394, 2006.
  • M. Pisu , N. Lai, A. Concas, G. Cao, A novel simulation model for engineered cartilage growth in static systems, Tissue Engineering, 12, 2311-2330, 2006.
  • Concas A., Lai N., Pisu M., Cao G., Modeling of comminution processes in spex mixer/mill, Chemical Engineering Science, vol.61, 3746-3760, 2006.
  • M. Pisu , N. Lai, A. Cincotti, A. Concas, G. Cao, Modeling of engineered cartilage growth in rotating bioreactors, Chemical Engineering Science, 59, 5035-5040, 2004.
  • M. Pisu, N. Lai, A. Cincotti, F. Delogu and G. Cao, A simulation model for the growth of engineered cartilage on polymeric scaffolds, International Journal of Chemical Reactor Engineering, Art38-Vol1, http://www.bepress.com/ijcre/vol1/A38, 2003.
  • A.Cincotti, N. Lai, R. Orru, and G. Cao, Sardinian Natural Clinoptilolites for Heavy Metals and Ammonia Removal: Experimental and Modeling, The Chemical Engineering Journal, 84, 275-282, 2001.
  • R. Orru, N. Lai, A. Cincotti, G. Cao, P. Accardo, M. Boi, and R. Lonis, Utilization of Sardinian Natural Clinoptilolites for Heavy Metals and Ammonia Removal, IEX2000, J.A. Greig (ed.), The Royal Society of Chemistry, Cambridge, 158-165, 2000.
See Proceedings
See Presentations & Abstracts
Memberships
  • American College of Sport Medicine (ACSM)
  • American Physiological Society (APS)
  • Biomedical Engineering Society (BMES)
  • International Society on Oxygen Transport to Tissue (ISOTT)