Search
Ilya Bederman, Ph.D.
Education
- 1991 Pharmacy
Moscow Pharmaceutical College, Moscow, Russia - 1998 BA Biochemistry
Case Western Reserve University - Department of Biochemistry - 2003 Ph.D. Nutritional Biochemistry
Case Western Reserve University - Department of Nutrition
Research Interests
- Stable Isotopes
- Intermediary Metabolism
- Energy Balance
Publications
- Gilge DA, Bederman IR, Ruszczycky MW, Anderson VE, Ernsberger P and Previs SF. Limiting the ion chromatogram integration improves gas chromatography-mass spectrometry measurements of 2H-labeling: Studying acute tissue-specific responses of protein synthesis. Journal of Mass Spectrometry, (Submitted), 2007.
- Previs SF, Bederman IR and Alexander JC. Extensive triglyceride synthesis in white adipose tissue in the absence of dietary carbohydrate: Evidence in support of glyceroneogenesis is limited by secondary tracers. Journal of Biological Chemistry (Submitted), 2007.
- Bederman IR and Previs SF. Hormonal regulation of intracellular lipolysis in diet-induced obesity. Metabolism (Submitted), 2007.
- Kang L, Chen X, Sebastian BM, Pratt BT, Bederman IR, Alexander JC, Previs, SF and Nagy LE. Chronic ethanol and triglyceride turnover in white adipose tissue in rats: Inhibition of the anti-lipolytic action of insulin after chronic ethanol contributes to increased triglyceride degradation. J of Biol. Chem. 282: 28465-28473. 2007
- Millward CA, Heaney JD, Sinasac DS, Chu EC, Bederman IR, Gilge DA, Previs SF and Croniger CM. Mice With a Deletion in the Gene for CCAAT/Enhancer-Binding Protein (beta) Are Protected Against Diet-Induced Obesity. Diabetes 56: 161-167, 2007.
- White NM, Jiang D, Burgess JD, Bederman IR, Previs SF and Kelley TJ. Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 2006.
- Bederman IR, Dufner DA, Alexander JC and Previs SF. Novel application of the "doubly labeled" water method: measuring CO2 production and the tissue-specific dynamics of lipid and protein in vivo. Am J Physiol Endocrinol Metab 290: E1048-E1056, 2006.
- McCabe BJ, Bederman IR, Croniger C, Millward C, Norment C and Previs SF. Reproducibility of gas chromatography-mass spectrometry measurements of 2H labeling of water: application for measuring body composition in mice. Anal Biochem 350: 171-176, 2006.
- Kasturi S, Bederman IR, Christopher B, Previs SF and Ismail-Beigi F. Exposure to azide markedly decreases the abundance of mRNAs encoding cholesterol synthetic enzymes and inhibits cholesterol synthesis. J Cell Biochem 2006.
- Dufner DA, Bederman IR, Brunengraber DZ, Rachdaoui N, Ismail-Beigi F, Siegfried BA, Kimball SR and Previs SF. Using 2H2O to study the influence of feeding on protein synthesis: effect of isotope equilibration in vivo vs. in cell culture. Am J Physiol Endocrinol Metab 288: E1277-E1283, 2005.
- Bederman IR, Kasumov T, Reszko AE, David F, Brunengraber H and Kelleher JK. In vitro modeling of fatty acid synthesis under conditions simulating the zonation of lipogenic [13C]acetyl-CoA enrichment in the liver. J Biol Chem 279: 43217-43226, 2004.
- Bederman IR, Reszko AE, Kasumov T, David F, Wasserman DH, Kelleher JK and Brunengraber H. Zonation of labeling of lipogenic acetyl-CoA across the liver: implications for studies of lipogenesis by mass isotopomer analysis. J Biol Chem 279: 43207-43216, 2004.
- Reszko AE, Kasumov T, Comte B, Pierce BA, David F, Bederman IR, Deutsch J, Des RC and Brunengraber H. Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry. Anal Biochem 298: 69-75, 2001.
- Puchowicz MA, Bederman IR, Comte B, Yang D, David F, Stone E, Jabbour K, Wasserman DH and Brunengraber H. Zonation of acetate labeling across the liver: implications for studies of lipogenesis by MIDA. Am J Physiol 277: E1022-E1027, 1999.