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Fatima Silva, Ph.D.

Education
  • 1980 BS Biological Science
    University of Moji das Cruzes, Sao Paulo, Brazil
  • 1991 MA Physiology/Pharmacology,
    Federal University of Sao Paulo - Dept. of Physiology, Brazil
  • 1996 PhD Physiology,
    Federal University of Sao Paulo - Dept. of Physiology, Brazil

Research Interests
  • Mechanisms involved in central regulation of airway and  cardiorespiratory functions.
  • Cardiovascular Exercise Physiology.
  • Exercise Training.
  • Exercise and transgenic mouse model of human disease.
Publications
  • Lai N., Nasca M., Silva M.A., Silva F.T., Whipp B.J. and Cabrera M.E., Influence of exercise intensity on pulmonary oxygen uptake kinetics at the onset of exercise and recovery in male adolescents Appl. Physiol. Nutr. Metab. 33(1): 107­117 (2008).
  • Hakimi P, Yang J, Casadesus G, Massillon D, Tolentino-Silva F, Nye CK, Cabrera ME, Hagen DR, Utter CB, Baghdy Y, Johnson DH, Wilson DL, Kirwan JP, Kalhan SC, Hanson RW. Over-expression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J. Biol. Chem. 282:32844-55, 2007.
  • Carvalho TH, Lopes OU, and Tolentino-Silva FR. Baroreflex responses in neuronal nitric oxide synthase knockout mice (nNOS). Autonomic Neuroscience-Basic & Clinical.126: 163-168, 2006.
  • Campos RR, Tolentino-Silva RF, and Mello LE Mello. Respiratory pattern in a rat model of epilepsy. Epilepsia, 44(5):712-717, 2003.
  • Kc P., Haxhiu MA, Tolentino-Silva, F.P., Wu M., Trouth CO, Mack SO. Paraventricular vasopressin-containing neurons projected to brain stem and spinal cord respiratory-related sites. Respiratory Physiology & Neurobiology. 23; 133(1-2):75, 2002.
  • Mack SO, Kc P, Wu M, Coleman BR, Tolentino-Silva FP, and M.A. Haxhiu. Paraventricular oxytocin neurons are involved in neural modulation of breathing. J. Appl Physiol. 92: 826-834, 2002.
  • Haxhiu MA, Tolentino-Silva F, Pete G, Kc P and Mack SO. Monoaminergic neurons, chemosensation and arousal. Respiration Physiology 129: 191-209, 2001.
  • Tolentino-Silva FP, Haxhiu MA, Waldbaum S, Dreshaj IA, and Ernsberger PR. µ2-Adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice. Brain Research 862: 26-35, 2000.
  • Tolentino-Silva FP, Haxhiu MA, Waldbaum S, Dreshaj IA, and Ernsberger PR. Differential cardiorespiratory control elicited by activation of two ventral medullary sites in mice. Journal of Applied Physiology 89: 437-44, 2000.
  • Liomar das Neves, Cynthia S. Duchala, F. Tolentino-Silva, Musa A. Haxhiu, Clemencia Colmenares, Wendy B. Macklin, Christine E. Campbell, Kenneth G. Butz, and Richard M. Gronostajski. Disruption of murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of corpus callosum. Proc. Natl. Acad. Sci (PNS) U S A. 96(21): 11946-51, 1999.
  • Tolentino-Silva FP, Russo AK, Cravo SL, and Lopes OU. Cardiorespiratory effects of kynurenic acid microinjected into the rat ventral medulla. Braz. J. Med. Res., 31(10): 1339-1343, 1998.
  • Tolentino-Silva FP, CamposRR, Russo AK, Cravo SL, and Lopes OU. Cardiorespiratory effects of L-glutamate microinjected into the rat ventral medulla. Resp. Physiol, 108: 23-33, 1997.
  • Tolentino-Silva FP, Campos RR, Russo AK, Silva AC, Freire E, and Guertzenstein PG. Cardiorespiratory alterations produced by pharmacological agents applied to the ventrolateral medulla (intermediate area) of the cat. Effect of exercise condition on glycine-induced inhibition. Braz. J. Med. Biol. Res., 26:879-896, 1993.
  • Rodrigues LO, Russo AK, Silva AC, Piçarro IC, Silva FRP Tolentino, Zogaib S, and Soares DD. Effects of caffeine on the rate of perceived exertion. Braz. J. Med. Biol. Res., 23:965-8, 1990.
  • Silva FRP Tolentino, Campos RR, Freire E, Guertzenstein PG, Piçarro IC, Rodrigues LO, Russo AK, Silva AC, and Tarasantchi J. Breathing pattern during pharmacological activation and blockade of the intermediate area of the ventrolateral surface of the cat medulla. Braz. J. Med. Biol. Res., 22:1527-1530, 1989.
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