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Welcome to the Electron Microscopy Facility

The Facility offers complete transmission electron microscopic services including sample processing, ultramicrotomy, film developing, and photographic printing, as well as immunocytochemistry.

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Welcome

The Electron Microscopy Core Facility provides critical ultrastructural skills, including immunocytochemistry, in addition to conventional EM techniques. The methodology can be tailored to specific needs. The Facility includes a FEI Tecnai G2 Twin Spirit (T12), 120kV, LaB6 filament, transmission electron microscope equipped with a Gatan US4000 (4kx4k) ultra-high sensitivity CCD camera, a fully equipped sample processing laboratory, a sectioning room, and a dark room.

The Facility offers complete transmission electron microscopic services including sample processing, ultramicrotomy, film developing, and photographic printing, as well as immunocytochemistry. Intramural collaboration is available. We welcome trained EM users as well as researchers who wish to be trained. For those workers who are not trained in ultrastructure, we additionally offer professional consultation or collaboration in interpretation of electron micrographs and in writing ultrastructural descriptions.

The EM Facility has received approval from the College of American Pathologists (CAP) and the Clinical Laboratory Improvement Amendments (CLIA) to provide the highest quality service to researchers at CWRU and pathologists at UH. An initial consultation with the Director is helpful to establish how we can best process and examine your particular specimen type. An innovative technical approach may be necessary for unusual types of research specimens. Consultation will provide a well-defined and efficient approach for individual research projects.

Isolated rat cardiac mitochondria. Bar=1µm.