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Sanjay Gupta, Ph.D.
Associate
Professor
Case Western Reserve University
11100 Euclid Avenue, Cleveland, OH 44106-4931
Phone: 216-368-6162, Fax: 216-368-0213
sanjay.gupta@case.edu
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Professional Experience
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2006- Associate
Professor, Department of Urology, Case School of Medicine |
2006- Associate
Professor with Sec. Appointment, Department of Nutrition, Division of General Medical Sciences , Case Comprehensive Cancer Center,
Case School of Medicine |
2002- Assistant
Professor, Department of Urology, Case School of Medicine |
2003- Assistant
Professor with Sec. Appointment, Division of General Medical Sciences , Case Comprehensive Cancer Center,
Case School of Medicine |
2001-02
Instructor, Department of Dermatology, Case School of Medicine |
Training
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Ph.D.:
1992 Avadh University, India |
Postdoctoral
Fellowship: 1993-95 King George's Medical College, India |
Postdoctoral
Fellowship: 1996-97 Industrial Toxicology Research Center, India |
Postdoctoral
Studies: 1997-00 Case Western Reserve University, USA |
Interests
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| Mechanism(s) of prostate carcinogenesis, Biomarker(s) for detection
of prostate cancer, Chemoprevention of prostate cancer by naturally occurring
and/or synthetic compounds |
Recent Publications
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| Gupta S, Adhami VM, Subbarayan M, MacLennan GT, Lewin JS, Hafeli
UO, Fu P, Mukhtar H. Suppression of prostate carcinogenesis by dietary
supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate
model. Cancer Res. 64: 3334-43, 2004 |
| Shukla S, Gupta S. Suppression of constitutive and tumor necrosis
factor alpha-induced nuclear factor (NF)-kappaB activation and induction of
apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with
down-regulation of NF-kappaB-responsive genes. Clin Cancer Res. 10: 3169-78,
2004 |
| Shukla S, MacLennan GT, Fu P, Patel J, Marengo SR, Resnick MI,
Gupta S. Nuclear factor-kappaB/p65 (Rel A) is constitutively activated in human
prostate adenocarcinoma and correlates with disease progression. Neoplasia. 6:
390-400, 2004 |
| Shukla S, Maclennan GT, Marengo SR, Resnick MI, Gupta S.
Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer
progression in autochthonous transgenic mouse model. Prostate 64:224-39, 2005 |
| Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, Gupta S.
Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads
to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice.
FASEB J. 19:2042-4, 2005 |
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