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case western reserve university

DEPARTMENT OF UROLOGY - FACULTY

 
 
 Sanjay Gupta, Ph.D. 

Sanjay Gupta, Ph.D.

Carter Kissell Associate Professor & Research Director

Case Western Reserve University
11100 Euclid Avenue, Cleveland, OH 44106-4931
Phone: 216-368-6162, Fax: 216-368-0213
sanjay.gupta@case.edu

Professional Experience

1 2008- Carter Kissell Associate Professor & Research Director, Department of Urology, Case School of Medicine
2 2006- Associate Professor, Department of Urology, Case School of Medicine
3 2006- Associate Professor with Sec. Appointment, Department of Nutrition, Division of General Medical Sciences , Case Comprehensive Cancer Center, Case School of Medicine
4 2002-06 Assistant Professor, Department of Urology, Case School of Medicine
5 2003-06 Assistant Professor with Sec. Appointment, Division of General Medical Sciences , Case Comprehensive Cancer Center, Case School of Medicine
5 2001-02 Instructor, Department of Dermatology, Case School of Medicine

Training

1 Ph.D.: 1992 Avadh University, India
2 Postdoctoral Fellowship: 1993-95 King George's Medical College, India
3 Postdoctoral Fellowship: 1996-97 Industrial Toxicology Research Center, India
4 Postdoctoral Studies: 1997-00 Case Western Reserve University, USA

Interests

Mechanism(s) of prostate carcinogenesis, Biomarker(s) for detection of prostate cancer, Chemoprevention of prostate cancer by naturally occurring and/or synthetic compounds

Recent Publications

  1. Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, Gupta S. Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice. FASEB J. 19:2042-4, 2005
  2. Shukla S, MacLennan GT, Flask CA, Fu P, Mishra A, Resnick MI, Gupta S. Blockade of beta-catenin signaling by plant flavonoid apigenin suppresses prostate carcinogenesis in TRAMP mice. Cancer Res. 67:6925-35, 2007
  3. Shukla S, Maclennan GT, Hartman DJ, Fu P, Resnick MI, Gupta S. Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion. Int J Cancer. 121:1424-32, 2007
  4. Shukla S, Gupta S. Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation. Free Radic. Biol. Med. 44:1833-45, 2008
  5. Vykhovanets EV, Shukla S, MacLennan GT, Resnick MI, Carlsen H, Blomhoff R, Gupta S. Molecular imaging of NF-kappaB in prostate tissue after systemic administration of IL-1 beta. Prostate. 68:34-41, 2008