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case western reserve university

DEPARTMENT OF UROLOGY - FACULTY

 
 
 Sanjay Gupta, Ph.D. 

Sanjay Gupta, Ph.D.

Associate Professor

Case Western Reserve University
11100 Euclid Avenue, Cleveland, OH 44106-4931
Phone: 216-368-6162, Fax: 216-368-0213
sanjay.gupta@case.edu

Professional Experience

1 2006- Associate Professor, Department of Urology, Case School of Medicine
2 2006- Associate Professor with Sec. Appointment, Department of Nutrition, Division of General Medical Sciences , Case Comprehensive Cancer Center, Case School of Medicine
3 2002- Assistant Professor, Department of Urology, Case School of Medicine
4 2003- Assistant Professor with Sec. Appointment, Division of General Medical Sciences , Case Comprehensive Cancer Center, Case School of Medicine
5 2001-02 Instructor, Department of Dermatology, Case School of Medicine

Training

1 Ph.D.: 1992 Avadh University, India
2 Postdoctoral Fellowship: 1993-95 King George's Medical College, India
3 Postdoctoral Fellowship: 1996-97 Industrial Toxicology Research Center, India
4 Postdoctoral Studies: 1997-00 Case Western Reserve University, USA

Interests

Mechanism(s) of prostate carcinogenesis, Biomarker(s) for detection of prostate cancer, Chemoprevention of prostate cancer by naturally occurring and/or synthetic compounds

Recent Publications

Gupta S, Adhami VM, Subbarayan M, MacLennan GT, Lewin JS, Hafeli UO, Fu P, Mukhtar H. Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 64: 3334-43, 2004
Shukla S, Gupta S. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes. Clin Cancer Res. 10: 3169-78, 2004
Shukla S, MacLennan GT, Fu P, Patel J, Marengo SR, Resnick MI, Gupta S. Nuclear factor-kappaB/p65 (Rel A) is constitutively activated in human prostate adenocarcinoma and correlates with disease progression. Neoplasia. 6: 390-400, 2004
Shukla S, Maclennan GT, Marengo SR, Resnick MI, Gupta S. Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model. Prostate 64:224-39, 2005
Shukla S, Mishra A, Fu P, MacLennan GT, Resnick MI, Gupta S. Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice. FASEB J. 19:2042-4, 2005