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A large portion of patients with diabetes also have urological complications, such as decreased bladder sensation, increased bladder capacity and urge incontinence. Through the Case Western Reserve University Interdisciplinary Research Center on Urological Complications of Obesity and Diabetes (UCOD), urology faculty members are examining mechanisms of diabetic bladder dysfunction to discover how to prevent or stop the development of urinary incontinence and poor bladder emptying in diabetic patients.

Center researchers also are:

  • characterizing bladder and urethral function over time in relation to hyperglycemia and obesity in a mouse model of type-2 diabetes mellitus (T2DM)
  • investigating the impact of obesity on continence recovery following vaginal distension injury in mice
  • studying the effects of T2DM and obesity on alterations of the prostate in a mouse model
  • identifying molecular targets responsible for time-course alterations of the bladder and prostate remodeling and function observed in a mouse model of T2DM

Learn more about faculty research programs in this area by clicking on the faculty member's name below.

Urological Complications of Diabetes and Obesity Research Faculty