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At Case Western Reserve University, the Department of Urology translational research team includes world-renowned basic scientists committed to preventing prostate cancer, bladder cancer and renal cancer. Currently, our researchers, in collaboration with colleagues at University Hospitals Urology Institute, are examining the chemo-preventive properties of green tea in preventing the spread of prostate cancer.

Additional basic, translational and clinical areas of cancer research being explored by our physicians and scientists include:

  • any associations between inflammation of the prostate gland and periodontal disease
  • potential biomarkers for early detection of prostate cancer
  • the effectiveness of PSA/SIA tests as prognostic markers for prostate cancer
  • the molecular mechanisms of chamomile tea in the prevention of prostate cancer
  • basic mechanisms and risk factors involved in the development of chronic prostatitis
  • the use of image-guided focal therapy for the treatment of prostate cancer
  • an animal model investigating the cancer-preventive potential of apigenin, a plant flavonoid found in common fruits and vegetables
  • the use of gene therapeutic techniques for treatment of bladder cancer
  • the deleterious effects of a high-fat diet on the prostate
  • the effects of cigarette smoking on immunotherapy for bladder cancer patients


Through the UH Urological Institute, Department of Urology physicians also actively pursue database studies to gather ongoing health data, such as medical and surgical outcomes. These database studies allow our physician researchers to formulate possible selection criteria for future cancer patients and to identify characteristics of our patients' diseases.


Department of Urology cancer research projects have received funding from National Cancer Institute, National Institutes of Health, National Center for Complementary and Alternative Medicine, Canadian Cancer Society and Analiza, Inc.


Learn more about faculty research programs in this area by clicking on the faculty member's name below.


Urological Cancer Research Faculty


Robert Abouassaly, MD, MS
Cengiz A. Altuntas, PhD
Magdalena M. Grabowska, PhD
Sanjay Gupta, PhD, MS
William Larchian, MD
Lee Ponsky, MD
Jonathan Ross, MD
Sanjeev Shukla, PhD
Lynn Woo, MD
Hui Zhu, MD
Craig Zippe, MD