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Welcome to campus

Visit Case Western Reserve University's uniquely urban campus, located in the heart of Cleveland's cultural hub, University Circle. Plan your trip:

Magdalena M. Grabowska, PhD

Education and Training

  • Postdoctoral Fellow, Urologic Surgery, Vanderbilt University, Nashville, TN
  • PhD, Cell and Molecular Biology, University of Michigan, Ann Arbor, MI
  • BA, Biochemistry and Molecular Biology, Boston University, Boston, MA

Research Interests

  • Prostate cancer

Biography

Dr. Grabowska is an Assistant Professor in the Department of Urology at Case Western Reserve University. Research in her laboratory is focused on understanding molecular mechanisms of prostate cancer progression. Currently, studies focus on how transcription factors, which bind to DNA and determine what genes are turned on or off, regulate prostate cancer. We are interested in how a specific transcription factor family, the nuclear factor I (NFI) family, interacts with androgen receptor, and how this interaction changes in response to prostate cancer therapy. Androgen receptor is the target of androgen deprivation therapy and the major therapeutic target in prostate cancer. Therefore, understanding how androgen receptor activity is regulated is critical for determining how patients fail androgen deprivation therapy. We are also interested in the androgen-independent roles of NFI family members, and how these can contribute to androgen receptor-independent prostate cancers. Our goal is to translate our basic science research into better outcomes for prostate cancer patients.


Research Team

  • Wisam Awadallah, BS: Research assistant
  • Jinlong Li: Undergraduate summer volunteer

Postdoctoral position available!

Interested candidates should send a cover letter, their CV, and contact information for three references to magdalena.grabowska@case.edu



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