Instructor - Martina Veigl
UCRC Bldg. 2, Suite 200
216-844-7525
| Lecture 1 & 2 | General
Introduction to Course UV Radiation Types of UV Radiation, Biological Effects of UV Radiation, Factors Affecting UV Exposure, Lesions at DNA Level, Repair of Lesion |
| Lecture 3 & 4 | Electromagnetic
Waves Sources and Levels of Exposure, Evaluate Danger of Exposure Ionizing Radiation Types of Radiation, Units of Radiation Measurement, Properties of Radionucleotides, Biological Effects of Radiation, Average Radiation Exposure and Sources of Radiation, Everyday Risks for Exposure to Radiation, Examples & Consequences of High Level Radiation Exposure, Ways to Monitor Radiation Exposure, Examples & Consequences of Low Level Radiation Exposure, Lesions at DNA Level, Repair of Lesions |
| Lecture 5 | Industrial Mutagens
- Dioxin, Polychlorinated Biphenyl, etc. Overview, Avenues of Exposure, Acute Toxicity, Genotoxicity |
| Lecture 6 & 7 | Health Effects of
Environmental Estrogens Classes will taught by Dr. Ellen Rorke |
| Lecture 8 | Cigarette Smoke Epidemiology Studies: Exposure and Genetic Susceptiblity, Mutation Studies in T-Lymphocytes in Smokers versus non-Smokers, Analysis of Mutation Profiles at the DNA Sequence Level, Reporter Gene in Tissue Culture Assays, Oncogenes from Tumor Tissues |
| Lecture 9 | SPRING BREAK |
| Lecture 10 | MIDTERM EXAM |
| Lecture 11 & 12 | Genotoxins and Food Sources of Potential Food Mutagens, Correlation Between Exposure and Disease, Analysis of DNA Adducts, Mutation Freq. & Mutation Types, Anticarcinogens, Epidemiology Studies: Genetic Susceptibility and Diet |
| Lecture 13 & 14 | Cytotoxicity and
Genotoxicity of Heavy Metals Properties of Lead, Chromium and Mercury are Reviewed, Physiologic Effects of Heavy Metals are Explored, Mutagenic Potential of these Heavy Metals in Standard Mutation Assays are Evaluated, Routes of Exposure - Chronic versus Acute Exposure |
| Lecture 15 & 16 | Microbial and Other
Infectious Agents Viruses [i.e. Hemorrhagic Fever, Ebola, etc.], Nosocomial Infections [i.e. Tuberculosis, etc.], Legionnaire's Disease, Development of Resistant Organisms |
| Lecture 17 | FINAL EXAM |