BLUEPRINT
MONDAY AUGUST 6 , 2007 4 FRIDAY OCTOBER 19, 2007
WEEK 1
PATTERNS OF IMMUNE SYSTEM FUNCTION
| Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
| Time |
AUGUST 6 |
AUGUST 7 |
AUGUST 8 |
AUGUST 9 |
AUGUST 10 |
8-10 AM |
Interactive
Sessions:
8-10 am
Introduction to Humoral and Cell-Mediated Immunity
1. Overview of innate / adaptive immunity |
Structure:
HP | Histology of Normal Hematopoietic Tissue
|
Interactive
Sessions:
8-9 am
HP | Lymphoid
Development
and Gene
Rearrangements
1. Ig and TCR gene
rearrangement, class switching, hypermutation
2. T&B cell lineage
3. Diseases associated with defects in development
9-10 am
Complement
Biochemistry
& Biology
1. Classical / alternative pathway & interaction with humoral immunity |
8-9 am
Block 5
Review
Session: Week 1 Patterns of Immune System Function
9-10 am
Structure:
HP REVIEW |
Review
Session |
Interactive Sessions:
Antibody Structure and Function
1. Ab structure
2. Ab/Ag complex formation
3. Principles of vaccination
9-10 am
Research & Scholarship |
10-12 Noon |
IQ Groups:
Case #1
Case #2 |
FCM - Foundations of
Clinical Medicine Blocks 5-6 |
IQ Groups:
Case #1
Case #2 |
Structure:
GAR
(REQUIRED) |
Anatomy of
the Vertebral
Column, Spinal
Cord & Back |
IQ Groups:
Case #1
Case #2 |
12-1 PM |
Noon - 2:30 pm
Orientation (Required)
|
|
|
|
Facilitators
Skill Session |
1-5 PM |
Clinical Skills 25% of Class / Self-Directed
Learning Time |
Clinical Skills 25% of Class / Self-Directed Learning Time |
Clinical Skills
25% of Class / Self-Directed
Learning Time |
Clinical Skills 25% of Class / Self-Directed Learning Time |
Self-Directed Learning
Time |
| 17 -19 PM |
|
Block 4 Review Session: Pulmonary (Optional)
Block 4 Review Session: Cardiology
(Optional) |
Block 4 Review Session: Renal (Optional)
Block 4 Review Session: Pharmacology
(Optional) |
|
|
TOP
WEEK 2
IMMUNITY AT THE MOLECULAR AND CELLULAR LEVEL
| Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
| Time |
AUGUST 13 |
AUGUST 14 |
AUGUST 15 |
AUGUST 16 |
AUGUST 17 |
| 8-10 AM |
Interactive
Sessions:
8-10 am
T cells and
Cell-Mediated Immunity
1. T cell lineage
2. CMI responses |
Structure:
GAR LAB| Lab
Dissections -
Dissection of
either Upper or
Lower Extremity
(Small Groups) |
Interactive
Sessions:
8-10 am
Hypersensitivity
& Autoimmunity
1. Mechanisms of immunopathology
(I-V)
2. Autoimmune disease processes
3. Genetic susceptibility to autoimmunity |
Block 5
Review
Session:
Week 2 Immunity at
the Molecular
& Cellular Level |
Interactive
Sessions:
Antigen Presenting Cells
and Innate Immunity
1. Mucosal immunity and the role of epithelial / chemical / microbial barriers
2. Macrophages / NK cells |
Research and
Scholarship
9-10 am |
| 10-12 Noon |
IQ Groups:
Case #3
Case #4 |
FCM - Foundations of
Clinical Medicine Blocks 5-6 |
IQ Groups:
Case #3
Case #4 |
Structure:
GAR | Lab
Review Session |
IQ Groups:
Case #3
Case #4
|
| 12-1 PM |
|
|
|
|
Facilitators
Skill Session |
| 1-5 PM |
Clinical Skills 25% of Class / Self-Directed Learning Time |
Clinical Skills 25% of Class / Self-Directed Learning Time |
Clinical Skills
25% of Class / Self-Directed
Learning Time |
Clinical Skills 25% of Class / Self-Directed Learning Time |
Self-Directed Learning Time |
TOP
WEEK 3
HEMATOPOIESIS AND THE HOST
| Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
| Time |
AUGUST 20 |
AUGUST 21 |
AUGUST 22 |
AUGUST 23 |
AUGUST 24 |
| 8-10 AM |
Interactive
Sessions:
8-9 am
Normal
Hematopoiesis / Anemia
Overview
1. Normal
hematopoieses and
the differentiation
from stem cells of
lymphocytes, rbcs,
granulocytes,
platelets,
macrophages /
monocytes- morphology of
differentiated cells
2. Hematopoietic sites in children and adults and the role
of the microenvironment,
stromal elements &
growth factors.
9-10 am
Micro /
Macrocytic
Anemias
|
Interactive
Sessions:
8-9 am
Hemolysis &
Basics of
Transfusion
Structure:
9-10 am
HP | Hemoglobino-
pathies / Thalassemia &
Abnormal Red
Cell Morphology
|
Interactive
Sessions:
8-9 am
Overview of
Thrombosis &
Hemostasis &
Approach to the
Bleeding Patient
9-10 am
Platelets, Thrombocytopenia
& von Willebrand Disease |
Block 5
Review Session:
Week 3 Hematopoiesis & the Host |
Interactive Sessions:
Thrombosis & Anticoagulation
|
Research and Scholarship
9-10 am |
| 10 AM- 12 Noon |
IQ Groups:
Case #5
Case #6 |
FCM - Foundations of
Clinical Medicine
Blocks 5-6
11-12 noon
Contraception 101: What it is & How it Works. . .
|
IQ Groups:
Case #5
Case #6 |
Structure:
HP REVIEW |
Week 3
Review Session |
IQ Groups:
Case #5
Case #6 |
| 12-1 PM |
|
|
|
|
Facilitators
Skill Session |
| 1-5 PM |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills
25% of Class /
Self-Directed Learning Time |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills 25% of Class /
Self-Directed
Learning Time |
Self-Directed
Learning Time |
TOP
WEEK 4
ABERRATIONS IN LYMPHOID DEVELOPMENT
Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
AUGUST 27 |
AUGUST 28 |
AUGUST 29 |
AUGUST 30 |
AUGUST 31 |
| 8-10 AM |
Structure:
8-9 am
HP | Granulocytes,
Lymphocytes &
Monocytes
9-10 am
HP | Pathology
of Lymphoma &
Lymphoid
Leukemia
|
Interactive
Sessions:
Lymphomas / Clinical
|
Interactive
Sessions:
8-9 am
Stem Cell
Disorders: Aplastic Anemia; Myelodysplastic Disorders; Myeloproliferative Disorders
9-10 am
Acute
Leukemias
1. Pathogenesis,
classification, clinical
manifestation &
natural hx of AML
and ALL
|
Structure:
8-9 am
HP | Week 4
Review
Session
9-11 am
Review
Session: Week 4 Aberrations in
Lymphoid
Development
|
Interactive
Sessions:
Plasma cell disorders
1. Pathogenesis, classification, clinical manifestation & natural hx of MM.
|
Research and Scholarship
9-10 am |
10 AM-
12 Noon |
IQ Groups:
Case #7
Case #8 |
FCM - Foundations of Clinical Medicine
Blocks 5-6
|
IQ Groups:
Case #7
Case #8 |
Structure Review
Session |
IQ Groups:
Case #7
Case #8 |
| 12-1 PM |
|
|
|
|
Facilitators
Skill Session |
| 1-5 PM |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills
25% of Class / Self-Directed
Learning Time |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills 25% of Class /
Self-Directed
Learning Time |
Self-Directed
Learning Time |
TOP
WEEK 5
BUGS AND DRUGS
| Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
SEPT. 3 |
SEPT. 4 |
SEPT. 5 |
SEPT. 6 |
SEPT. 7 |
8-10 AM |
LABOR DAY
HOLIDAY |
Structure:
GAR LAB | Dissection - Upper & Lower Extremities
|
Interactive
Sessions:
8-9 am
Prokaryotic
Organization
1. Classification of
pathogenic bacteria
(GPC, GPR, GNC,
GNR, anaerobes,
intracellular
pathogens)
9-10 amAntibiotics as
a Window to
Understanding
Microbial
Physiology
1. Targets &
mechanisms of
antibiotic therapy.
2. Indications and
use of antibiotics.
|
Block 5
Review Session:
Week 5
Bugs & Drugs |
Interactive
Sessions:
Mechanisms
of Antibiotic
Resistance
1. Bacterial, host &
environmental
factors causing
antimicrobial
resistance.
|
Research and
Scholarship
9-10 am
|
10 AM-
12 Noon |
|
FCM -
Foundations of
Clinical Medicine
Blocks 5-6
|
IQ Groups:
Case #9 |
Structure:
GAR REVIEW |
Week 5
Review Session |
IQ Groups:
Case #9 |
12-1 PM |
|
|
|
|
Facilitators
Skill Session |
1-5 PM |
Clinical Skills 25% of Class /
Self-Directed
Learning Time |
Clinical Skills
25% of Class /
Self-Directed
Learning
Time |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills 25% of Class /
Self-Directed
Learning Time |
Self-Directed
Learning Time |
TOP
WEEK 6
CLINICAL SYNDROMES AND MAJOR MICROBIAL PATHOGENS I
Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
SEPT. 10 |
SEPT. 11 |
SEPT. 12 |
SEPT. 13 |
SEPT. 14 |
8-10 AM |
Interactive
Sessions:
9-10 amMicrobiology /
Bacteriology -
Sepsis
1. Bacteriologic
Clinical Syndromes -
Meningitis
9-10 am
Complicated Skin &
Soft Tissue Infection
|
Structure:
GAR/HP |
Infection & Inflammation
1. Gram Stains
2. EM
3. Anatomic and
X-ray correlations
with infections
(including TB, fungal,
bacterial and viral
pathogens)
Histopathologic
examples of
Parasitology,
including
malaria.
|
Interactive
Sessions:
8-9 am
Tuberculosis
1. Epidemiology of TB
and the interactions
of TB and HIV.
9-10 am
Fungal Infections
1. Pathogenesis,
microbial & host susceptibility factors,
clinical manifestations
& treatment.
|
Block 5
Review Session:
Week 6 Clinical
Syndromes &
Major Microbial Pathogens I |
Interactive
Sessions:
DNA Viruses,
HSV
|
Research and
Scholarship
9-10 am
|
10 AM-
12 Noon |
IQ Groups:
Case #10
Case #11 |
FCM - Foundations of
Clinical Medicine
Blocks 5-6
|
IQ Groups:
Case #10
Case #11 |
Structure:
HP REVIEW | Week 6 Review
Session |
IQ Groups:
Case #10
Case #11 |
12-1 PM |
|
|
|
|
Facilitators
Skill Session |
1-5 PM |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills
25% of Class /
Self-Directed
Learning Time |
Clinical Skills 25% of Class /
Self-Directed
Learning Time |
Self-Directed
Learning Time |
TOP
WEEK 7
MAJOR MICROBIAL PATHOGENS II
Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
SEPT. 17 |
SEPT. 18 |
SEPT. 19 |
SEPT. 20 |
SEPT. 21 |
8-10 AM |
Interactive
Sessions:
8-9 am
RNA Viruses: Influenza
9-10 am
Malaria
1. Epidemiology,
patho-genesis
including parasite
life-cycle, clinical
manifestations,
diagnosis &
treatment. |
Structure:
GAR | Critical Extremity
Anatomy; The Somatosensory Pathyways
|
Interactive
Sessions:
8-10 am
HIV
1. Pathogenesis and virology
|
Block 5
Review Session:
Week 7 Major
Microbial
Pathogens II
|
Interactive
Sessions:
International
Medicine
|
Research and
Scholarship
9-10 am
|
10 AM-
12 Noon |
IQ Groups:
Case #12
Case #13 |
FCM -
Foundations of
Clinical Medicine
Blocks 5-6
|
IQ Groups:
Case #12
Case #13 |
Structure:
GAR REVIEW |
Week 7
Review Session |
IQ Groups:
Case #12
Case #13 |
12-1 PM |
|
|
|
|
Facilitators
Skill Session |
1-5 PM |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Self-Directed
Learning Time |
TOP
WEEK 8
CLINICAL IMMERSION
DRAFT
Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
SEPT. 24 |
SEPT. 25 |
SEPT. 26 |
SEPT. 27 |
SEPT. 28 |
8-12 NOON |
2/3 of class broken into groups going to UH, VA. Metro, CC etc. to visit patients with Acute Infection or Disease, HIV/TB Clinics, & Rheum Clinics |
2/3 of class broken into groups going to UH, VA. Metro, CC etc. to visit patients with Acute Infection or Disease, HIV/TB Clinics, & Rheum Clinics
|
2/3 of class broken into groups going to UH, VA. Metro, CC etc. to visit patients with Acute Infection or Disease, HIV/TB Clinics, & Rheum Clinics
|
A session analogous to our current
4 hour
Metro Day where
students have contact with Rheumatology / Dermatology patients with autoimmune disease.
|
Presentations and Discussion
|
1/3 of class: At SOM learning to take sexual history OR at Health Dept, etc. learning about ID issues |
1/3 of class: At SOM learning to take sexual history OR at Health Dept learning about ID issues |
1/3 of class: At SOM learning to take sexual history OR at Health Dept learning about ID issues |
12-1 PM |
|
|
|
|
|
1-5 PM |
2/3 of class broken into groups going to UH, VA. Metro, CC etc. to visit patients with Acute Infection or Disease, HIV/TB Clinics, & Rheum Clinics |
2/3 of class broken into groups going to UH, VA. Metro, CC etc. to visit patients with Acute Infection or Disease, HIV/TB Clinics, & Rheum Clinics |
2/3 of class broken into groups going to UH, VA. Metro, CC etc. to visit patients with Acute Infection or Disease, HIV/TB Clinics, & Rheum Clinics |
Students will also be exposed to small group sessions to process the information gained on Rheumatology / Dermatology Trip. |
|
1/3 of class: At SOM learning to take sexual history OR at Health Dept etc. learning about ID issues |
1/3 of class: At SOM learning to take sexual history OR at Health Dept learning about ID issues |
1/3 of class: At SOM learning to take sexual history OR at Health Dept learning about ID issues |
WEEK 9
THE BALANCE BETWEEN SELF AND NON-SELF
Intro to Autoimmunity posters (Vasculitis, Inflammatory arthritis, SLE). Posters to be left in study room.
-
To describe pathological, radiographic, and laboratory abnormalities typically seen during chronic tissue specific inflammation of joints.
-
What are the clinical characteristics unique to ankylosing spondylitis? Contrast ankylosing spondylitis, Rheumatoid Arthritis, and SLE.
-
Describe at least five physical findings in a patient with new onset fatigue and fever that would make you concerned about the possibility of systemic lupus erythematosus.
Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
OCTOBER 1 |
OCTOBER 2 |
OCTOBER 3 |
OCTOBER 4 |
OCTOBER 5 |
8-10 AM |
Interactive
Sessions:
8-8:15 am
Overview of
Rheumatology
Week
8:15-9:20 amSystemmic
Lupus
Erythematosus,
Sclerodeerma,
Diagnostic
Autoimmune
Laboraatory
Tests
9:20-9:50 amAnkylosing
Spondylitis &
Related Spondylo-
arthropathies
Describe genetic
susceptibility at the
MHC Class I locus,
and correlate
this with the genetic association of HLA-B27
with ankylosing spondylitis and related diseases (spondylo-arthropathies),
|
Structure:
GAR | Anatomy
in Clinical Cases
with Orthopedic
Residents,
Cervical Spine
& Upper
Extremity
|
Interactive
Sessions:
8-9 am
Pediatric Rheumatology
9-9:30 am
Sjogrens Syndrome
9:30-10:00 am
Inflammatory Myopathies
|
Block 5
Review
Session:
Week 9
The Balance
Between Self & Non-Self
|
Interactive
Sessions:
Vasculitis
1. To list 3 clinical
clues to guide the
clinician to consider
vasculitis.
2. To identify
three possible triggers
of vasculitis, the
pathology that is
found following these
triggers, and the mechanism linking
these triggers to
disease pathogenesis.
3. Name three
vasculitic diseases
and describe the
histological
appearance
of the associated
lesions:
include one in which
antibody is actively
deposited in the
lesion,
one which has
granulomas and one
in which giant cells
are found.
4. Name 3 of the
diagnostic tests to
facilitate a work up
for vasculitis, and
describe the value of each test in the
diagnosis of
vasculitis
|
Research and Scholarship
9-10 am
|
10 AM-
12 Noon |
IQ Groups:
Case #14
Case #15 |
FCM - Foundations of
Clinical Medicine
Blocks 5-6
|
IQ Groups:
Case #14
Case #15 |
Structure:
GAR | Anatomy
in Clinical
Cases with
Orthopedic
Residents,
Lumbar Spine
& Lower
Extrtemity |
IQ Groups:
Case #14
Case #15 |
12-1 PM |
|
|
|
|
Facilitators
Skill Session |
1-5 PM |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills 25% of Class/
Self-Directed Learning Time |
Self-Directed
Learning Time |
TOP
WEEK 10
SKIN AS A WINDOW TO THE IMMUNE SYSTEM AND
A BARRIER TO INFECTION
Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
OCTOBER 8 |
OCTOBER 9 |
OCTOBER 10 |
OCTOBER 11 |
OCTOBER 12 |
8-10 AM |
Interactive
Sessions:
Inflammatory
Skin Diseases
1. Mucosal immune
responses
2. Immunopatho-logic
responses in the skin. |
Structure:
HP | Skin
Histopathology
|
Interactive
Sessions:
8-9 am
Skin Cancer
9-10 am
Bullous Diseases
|
Clinical Session:
Metro Trip
(REQUIRED)
(7 am bus
departure time)
|
Review
Session:
Week 10
Skin as a
Window to
the Immune System and
Barrier to
Infection
|
10 AM-
12 Noon |
IQ Groups:
Case #16 |
FCM - Foundations of
Clinical Medicine
Blocks 5-6
|
IQ Groups:
Case #16 |
Structure:
10-11 am
HP REVIEW | Week 10 Review Session
11-12 noon
GAR REVIEW | Week 10
Gross
Anatomy & Neuroanatomy |
12-1 PM |
|
|
|
|
Facilitators
Skill Session |
1-5 PM |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills
25% of Class/
Self-Directed
Learning Time |
Clinical Skills 25% of Class/
Self-Directed Learning Time |
Self-Directed
Learning Time |
TOP
WEEK 11
REFLECTION AND INTEGRATION
Day |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Time |
OCTOBER 15 |
OCTOBER 16 |
OCTOBER 17 |
OCTOBER 18 |
OCTOBER 19 |
9-10 AM |
9-10 am
Block 5
Review
Session #1:
Rheumatology |
Structure:
Practical
Examinations |
Block 5
Review
Session #4:
Immunology
|
Summative
Synthesis Essay
Question
(SSEQ) Examination
Test starts promptly at
8:00 am
|
9-10 am
Introduction to
Block 6
|
10 AM-
12 Noon |
Review
Session #2:
ID- Microbiology |
FCM -
Foundations of
Clinical Medicine
Blocks 5-6
|
|
|
|
12-2 PM |
|
Block 5
Review
Session #3:
Heme/Onc |
|
|
|
1-5 PM |
1 - 3 pm
GAR | Anatomy
Review Session |
|
|
|
NBME Cumulative Achievement Examination |
TOP
|
