Clinical Research Units Services (CRUS)

NEW: NIH changes requirements for use of Clinical Research Unit Services

The Clinical Research Units (CRU) are committed to providing your study teams with quality research services. Nationally, NIH is changing the source of funds for CRU services. Over the past 50+ years, NIH funded the provision of centralized research-dedicated facilities, as well as research professionals in nursing, lab and bionutrition, most recently via the NCATS CTSC infrastructure grant. Over the next 2 years, the CRU teams will work with investigators to transition funding for those services into the investigators' individual grant applications. While we have this transition period until the NIH changes are fully implemented, as of July 1, 2015, we request all investigators, regardless of funding mechanism, contact their CRU administrator to determine CRU-specific budgets for inclusion in grant proposals. Click here for information and FAQs.

The CRUS provides highly experienced staff and dedicated research facilities for the conduct of clinical and translational studies. The focus of the CRUS is to provide safe, controlled and supportive research environments for adult and pediatric projects. Facilities are associated with each of the 3 CTSC partner institutions — The Cleveland Clinic, MetroHealth and University Hospitals -- and are available to both junior and senior investigators.

Research resources are customized to meet investigator needs and include:

  • Facilities: inpatient, outpatient and community-based;
  • Staffing: research-trained nurses, bionutritionists, lab personnel and study coordination staff offer facility-based or deployable services;
  • Services include:
    • Bionutrition: anthropometrics (neonatal specialty), metabolic kitchen, dietary recall using NDSR
    • Lab: sample processing & shipping, research analytical services
    • Informatics: REDCap database development, Explorys training
    • Fee-for-service study coordinator services

The CRUS administrators at each of the 3 institutions collaborate with their respective institutions' Research Administration office to support investigators and their teams through the entire research process – project start-up through completion.


To discover how the CRUS may assist with your research project, please contact the administrator at your institution:


  • W. H. Wilson Tang, MD, Co-Director
  • Charlotte Bhasin, Administrator
  • Email:
  • Telephone: 216-444-5113


  • Patrick Catalano, MD - Co-Director
  • Noreen Roman - Administrator
  • Telephone: 216-778-3130