2016 Awardees

The CTSC has provided pilot research funding to investigators and scholars.

The Clinical and Translational Science Collaborative is pleased to announce the awarding of the 2016 Pilot Project Awards to clinical and translational investigators of Case Western Reserve University, and its partner institutions.




Annual Pilot Awardees


Name Institution Project Title Amount
Chaitra Badve UHCMC Magnetic Resonance Fingerprinting of Glioblastoma Multiforme for Quantitative Characterization of Tumor Microenvironment $46,011.08
Susann Brady-Kalnay CWRU SOM PTPmu Targeting of Nanobubbles and Ultrasound Guided Therapy for Ovarian Cancer $50,000.00
Darlene Lobel CCLCM Virtual Reality Based Rehabilitation in Subacute Spinal Cord Injury $49,633.90
Jonathan Pokorski CWRU Eng Dissolving Microneedles for Sustained Insulin Delivery $45,526.00
James Rowbottom UHCMC Development of a Catheter Injection Port Cleaner $29,882.00
Jayakumar Sahadevan VAMC Cardiac Mapping for the Treatment of Atrial Fibrillation $50,000.00
Marion Skalweit VAMC The Effect of Opportunistic Infection (OI) Prophylaxis on the Intestinal Microbiome and Immune Reconstitution in Patients with HIV and AIDS $28,852.67

Core Utilization Awardees


Name Institution Project Title Amount
Ozan Akkus CWRU A Biologic Antimicrobial Coating for Implantable Hardware $10,000.00
Eben Alsberg CWRU BME Effects of Construct Geometry on Stem Cell-mediated Functional Bone Regeneration $9,750.00
Tracey Bonfield CWRU-SOM Development of Acetaminophen and Allergy $10,000.00
David Buchner CWRU SOM Genetics of Pediatric Endocrinology Disease $9,650.00
Jeffrey Capadona CWRU-BME Investigation of Gene Expression Profiles Surrounding Intracortical microelectrodes $10,000.00
James Chmiel UHCMC Mesenchymal Stem Cells in CF: A Phase I Single Center Safety Study $10,000.00
Arlene Dent UHCMC Characterization of Immune Complexes in Malaria Disease $10,000.00
Katherine Dobbs UHCMC Epigenetic Reprogramming of Monocytes During Malaria Infection in Children $6,819.00
Mirela Dobre UHCMC Alkali Therapy Effect on the Cardiac Fibrosis in Patients with Chronic Kidney Disease $9,840.00
Jennifer Dorth UHCMC Murine Model of the Pathophysiology of Radiation-Induced Vascular Injury $9,980.00
Vanessa Ho UHCMC Morbidity and Mortality as a Function of Preexisting Multimorbidity Following Emergency Surgery in Geriatric Cancer Patients $10,000.00
Trevor Jenkins UHCMC S-Nitrosylation of Augment Acclimation to Acute Hypoxia $10,000.00
Emmitt Jolly CWRU SOM Identification of lincRNAs in Human Schistosomes $9,940.00
Ahmad Khalil CWRU-SOM Functional Analysis of the DNMT1-associated lincRNA DACOR1 in Colon Cancer $10,000.00
Christopher King CWRU SOM MicroRNAs as Biomarkers and Regulators of Immune Response in Human Cord Blood $9,940.00
Zhenghong Lee CWRU BME Transcriptome-wide Analysis of lncRNAs and mRNAs in Nasal vs. Articular Cartilage in Humans $10,000.00
Yan Li CWRU SOM Highly Parallel Single-cell Transcriptome Analysis in Human Islets and Pancreatic Cell Fate Determination $10,000.00
Elizabeth Madigan CWRU-SON Transitions of care for persons undergoing hip and knee replacement $10,000.00
Indu Malhotra CWRU SOM Effect of Antenatal Maternal Infections and Anemia on Childhood Anemia $9,904.00
Shigemi Matsuyama UHCMC Mechanism of Cell Death Regulation by Bax and Bak $10,000.00
Thomas McIntyre CCLCM Activity-based ADAMDEC1 Inhibitors $6,365.00
Leland Metheny UHCMC The Relation Between Obesity, Cytokines, Disease Status and Outcomes in Patients Undergoing Autologous HCT for Myeloma $10,000.00
Anita Misra-Hebert CCLCM Assessment of Prostate Cancer Screening with the Prostate Specific Antigen in Cleveland Clinic Health System Primary Care Practices: Rates and Provider Variation 2007-2015 $10,000.00
William Schiemann CWRU-SOM Mapping the Transcriptome in Dormant Breast Cancer Stem Cells $10,000.00
David Serre CCLCM Development of a Novel Sequencing Approach to Quantify DNA Chemical Modifications in the Human Genome $8,400.00
Steven Shein UHCMC Ipatropium in Pediatric Status Asthaticus - A Secondary Analysis of the OPAR Database $8,100.00
Jerry Silver CWRU SOM A RTN/pFRG-Specific CRE Mouse for Redefining Respiratory Rhythm Generation $7,100.00
Nora Singer MHMC Seeking Regulatory Approval for a Phase I Concept Clinical Trial of Cell-based Therapy in Rheumatoid Arthritis $10,000.00
James Voos UHCMC Use of Autologous Expanded Mesenchymal Stem Cells for the Treatment of Early Osteoarthritis and Focal Chondral Defects of the Knee (Phase I) $10,000.00
Bing-Chen Wang MHMC Regulation of Cutaneous Tumor Progression by EphA2/Ephrin-A System $10,000.00
Richard Wilson MHMC Peripheral Nerve Stimulation + Physical Therapy for Hemiplegic Shoulder Pain $10,000.00
Michael Wolfe MHMC Effect of GIP Monoclonal Antibody on Behavior in the Mouse $10,000.00
Chad Zender UHCMC Analysis of Human Beta Defensin 2 (hBD2) and Human Beta Defensing 3 (hBD3) Expression in Keratinocytes in Human Oral Mucosal Epithelium Using LASER Capture Microdissection (LCM) $10,000.00
Youwei Zhang CWRU SOM Roles of UbcH7 in Tumorigenesis and Therapy $4,500.00
Jianjun Zhao CCLCM Identification of Secreted Exosomes as Biomarker for Multiple Myeloma Progression $10,000.00