Past Developmental Awardees

The Center For AIDS Research is pleased to recognize the following CFAR members that were awarded past Developmental Awards. The Developmental Award is available to provide funding for new HIV/AIDS research projects, funds are made available for studies that enhance interactions between scientists and for support of technological developments.


Fengchun Ye, Ph.D., CWRU Dental School

Epigenetic regulation of viral replication by periodontal bacteria

Blanton Tolbert, Ph.D., CWRU Department of Chemistry

Biophysical and biochemical approaches to investigate control of HIV transcription by 7SK snRNA


Arlene Dent, M.D., Ph.D., Case Pediatrics

B cell development in HIV exposed but uninfected Kenyan infants

Kurt Lu, M.D. Case Department of Dermatology

A novel method to enhance M. tuberculosis clearance by promoting phagosome-lysosome fusion in macrophages using statins and rosiglitazone


Gareth Hardy, Ph.D., Case Department of Pathology

Role of type-I IFN and TLR-ligands in T cell activation during HIV-1 infection

Roxana Rojas, Ph.D., Case Case Division of Infectious Diseases

Molecular mechanisms of mycobacterium tuberculosis induced HIV-1 replication

John (Chip) Tilton, M.D., Case Department of Proteomics and Bioinformatics

Effects of chronic immune activation on CD4+ T cell susceptibility to HIV infection


Allison Webel Ph.D., Case School of Nursing

SystemCHANGE-HIV: A pilot study exploring the effect of a systems-based intervention to increase physical activity, sleep behavior and mental wellness

Patrick Wintrobe, Ph.D., Case Department of Physiology and Biophysics

Solution conformation and interactions of the full length HIV-1 Gag polyprotein


Helene Bernstein, M.D., Ph.D., University Hopsital Division on Maternal Fetal Medicine

The Role of the Innate Immune System in Preventing Perinatal HIV Transmission

Liem Nguyen, Ph.D., Case Department of Molecular Biology and Microbiology

A Phenogenotypic Circuitry Controlling Host Persistence and Folate-Dependent Biofilm Growth in Mycobacteria Reveals Novel Strategies for Tuberculosis Chemotherapy

Lance Vernon, DMD, MPH, Case Department of Biological Sciences

Immune and Inflammatory Consequences of Aggressive Periontal Treatment in HIV+ Subjects

Gopala Yadavalli, M.D., Case Department of Medicine

Pilot Study of Hyperimmune Bovine Colostrum in Untreated, HIV-Infected Persons


David McDonald, Ph.D., Department of Molecular Biology and Microbiology

The role of dendritic cell-mediated HIV transmission in lymphoid tissues

Charles Mahan, Ph.D.

Role of IL-7R (CD127) expression on CD4 and CD8 T cells as a predictor of immunologic and virologic response to combined HIV/TB therapy in HIV/TB co-infected persons in Uganda

Yong Gao, Ph.D., Case Department of Medicine

A model for generation of diverse HIV-1 envelopes within chimeric, non-infectious viruses through intersubtype recombination: Development of polyvalent HIV-1 vaccines


Rajeev Mehlotra, Ph.D.,Case Global Health & Diseases

Genetic Basis of Variation in Human Antiretroviral Drug Metabolism

Liem Nguyen, Ph.D.,  Case Department of Molecular Biology and Microbiology

Persistence of Pathogenic Mycobacteria in Dendritic Cells and Reactivation by Effectors of HIV-mediated Immune Dysfunction

Scott Sieg, Ph.D., Case Division of Infectious Diseases

Naive regulatory T cells in HIV


Koh Fujinaga, Ph.D., Case Division of Infectious Diseases

Evaluation of the role of NELF in the establishment of HIV latency

David Canaday, M.D., Case Division of Infectious Diseases

Antigen Processing in HIV-infected Individuals

Patrick Wintrode, Ph.D., Case Dept. of Physiology and Biophysics

The Influence of Non-Nucleoside Inhibitors on the Conformational Dynamics of HIV-1 Reserve Transcriptase and its Drug Resistant Mutations


Ajay Sethi, Ph.D., Department of Epidemiology and Biostatistics

Development of Simple Tools to Assess ART Adherence in Brazil

Donald Anthony, M.D., Ph.D., Institute of Pathology

Immunity of neoantigen response in HCV, HIV, and HCV-HIV

Marion Helfand, M.D., Cleveland Veterans Administration Medical Center

Raman Crystallography of Resistant HIV Protease Enzymes: why do flap mutations cause drug resistance?

David McDonald, Ph.D., Department of Molecular Biology and Microbiology

Cell Biology of HIV/Mtb co-infection


Michael Cho, Ph.D., Department of Infectious Diseases

Eliciting broadly neutralizing antibodies against HIV-1

Young Kyeung Kim, Ph.D., Department of Molecular Biology & Microbiology 

NF-kappB activation of HIV transcription in latently infected T-cells

Jackson Orem, MB, ChB, Uganda Cancer Institute

Pilot study of Indinavir in the treatment of endemic Kaposi's sarcoma in Uganda


Scott Sieg,  Ph.D., Division of Infectious Diseases

Relationship between CD4+ T cell proliferation function and immune responses to vaccination in HIV-infected patients

Christina  Hirsch, M.D., Ph.D., Division of Infectious Diseases

CD4 cell apoptosis and T cell responses in HIV/TB

Koh Fujinaga,  Ph.D., Division of Infectious Diseases

Establishment of an efficient screening method for inhibitors of HIV  transcription


Miguel Quinones, Ph.D.

Lethal mutagenesis as a new antiretroviral strategy

David  Canaday, M.D., Case Division of Infectious Diseases

Effects of HIV-1 on MHC-II antigent processing in monocytes