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Notable News

  • New Publication

    Funderburg NT, Xu D, Playford MP, Joshi AA, Andrade A, Kuritzkes DR, Lederman
    MM, Mehta NN. Treatment of HIV infection with a raltegravir-based regimen
    increases LDL levels, but improves HDL cholesterol efflux capacity. Antivir Ther.
    2017;22(1):71-75. doi: 10.3851/IMP3091. Epub 2016 Oct 14. PubMed PMID: 27740536;
    PubMed Central PMCID: PMC5516727.

  • New Publication

    Muzaale AD, Althoff KN, Sperati CJ, Abraham AG, Kucirka LM, Massie AB,
    Kitahata MM, Horberg MA, Justice AC, Fischer MJ, Silverberg MJ, Butt AA, Boswell
    SL, Rachlis AR, Mayor AM, Gill MJ, Eron JJ, Napravnik S, Drozd DR, Martin JN,
    Bosch RJ, Durand CM, Locke JE, Moore RD, Lucas GM, Segev DL. Risk of End-Stage
    Renal Disease in HIV-Positive Potential Live Kidney Donors. Am J Transplant. 2017
    Jul;17(7):1823-1832. doi: 10.1111/ajt.14235. Epub 2017 May 12. PubMed PMID:
    28497525; PubMed Central PMCID: PMC5489376.

  • New Publication

    Nixon DE, Bosch RJ, Chan ES, Funderburg NT, Hodder S, Lake JE, Lederman MM,
    Klingman KL, Aberg JA; AIDS Clinical Trials Group Study A5275 Team. Effects of
    atorvastatin on biomarkers of immune activation, inflammation, and lipids in
    virologically suppressed, human immunodeficiency virus-1-infected individuals
    with low-density lipoprotein cholesterol <130 mg/dL (AIDS Clinical Trials Group
    Study A5275). J Clin Lipidol. 2017 Jan - Feb;11(1):61-69. doi:
    10.1016/j.jacl.2016.09.017. Epub 2016 Oct 5. PubMed PMID: 28391912; PubMed
    Central PMCID: PMC5407297.

  • New Publication

    Bonar MM, Tilton JC. High sensitivity detection and sorting of infectious
    human immunodeficiency virus (HIV-1) particles by flow virometry. Virology. 2017
    May;505:80-90. doi: 10.1016/j.virol.2017.02.016. Epub 2017 Feb 21. PubMed PMID:
    28235684; PubMed Central PMCID: PMC5393045.

  • New Publication

    Garcia-Mesa Y, Jay TR, Checkley MA, Luttge B, Dobrowolski C, Valadkhan S,
    Landreth GE, Karn J, Alvarez-Carbonell D. Immortalization of primary microglia: a
    new platform to study HIV regulation in the central nervous system. J Neurovirol.
    2017 Feb;23(1):47-66. doi: 10.1007/s13365-016-0499-3. Epub 2016 Nov 21. PubMed
    PMID: 27873219; PubMed Central PMCID: PMC5329090.

  • New Publication

    Al-Kindi SG, Kim CH, Morris SR, Freeman ML, Funderburg NT, Rodriguez B,
    McComsey GA, Dalton JE, Simon DI, Lederman MM, Longenecker CT, Zidar DA. Brief
    Report: Elevated Red Cell Distribution Width Identifies Elevated Cardiovascular
    Disease Risk in Patients With HIV Infection. J Acquir Immune Defic Syndr. 2017
    Mar 1;74(3):298-302. doi: 10.1097/QAI.0000000000001231. PubMed PMID: 27828877;
    PubMed Central PMCID: PMC5303143.

  • New Publication

    Al-Kindi SG, Zidar DA, McComsey GA, Longenecker CT. Association of
    Anisocytosis with Markers of Immune Activation and Exhaustion in Treated HIV.
    Pathog Immun. 2017;2(1):138-150. doi: 10.20411/pai.v2i1.199. Epub 2017 May 2.
    PubMed PMID: 28713869; PubMed Central PMCID: PMC5505669.

  • New Publication

    Fatukasi TV, Cole SR, Moore RD, Mathews WC, Edwards JK, Eron JJ; CNICS
    investigators. Risk factors for delayed antiretroviral therapy initiation among
    HIV-seropositive patients. PLoS One. 2017 Jul 10;12(7):e0180843. doi:
    10.1371/journal.pone.0180843. eCollection 2017. PubMed PMID: 28700693; PubMed
    Central PMCID: PMC5507276.

  • New Publication

    Drozd DR, Kitahata MM, Althoff KN, Zhang J, Gange SJ, Napravnik S, Burkholder
    GA, Mathews WC, Silverberg MJ, Sterling TR, Heckbert SR, Budoff MJ, Van Rompaey
    S, Delaney JAC, Wong C, Tong W, Palella FJ, Elion RA, Martin JN, Brooks JT,
    Jacobson LP, Eron JJ, Justice AC, Freiberg MS, Klein DB, Post WS, Saag MS, Moore
    RD, Crane HM. Increased Risk of Myocardial Infarction in HIV-Infected Individuals
    in North America Compared With the General Population. J Acquir Immune Defic
    Syndr. 2017 Aug 15;75(5):568-576. doi: 10.1097/QAI.0000000000001450. PubMed PMID:
    28520615; PubMed Central PMCID: PMC5522001.

  • New Publication

    Belaunzarán-Zamudio PF, Azzoni L, Canaday DH, Caro-Vega YN, Clagget B, Rassool
    MS, Rodriguez B, Sanne I, Sereti I, Sierra-Madero JG, Lederman MM. Immunologic
    Effects of Maraviroc in HIV-Infected Patients with Severe CD4 Lymphopenia
    Starting Antiretroviral Therapy: A Sub-Study of the CADIRIS Trial. Pathog Immun.
    2017;2(2):151-177. doi: 10.20411/pai.v2i2.181. Epub 2017 May 9. PubMed PMID:
    28736763; PubMed Central PMCID: PMC5518704.

  • CWRU researcher receives 3.9 million dollar grant for innovative HIV research

    Alan Levine awarded grant to determine if the combination of the human immunodeficiency virus (HIV) and drug abuse is a double kick in the gut.

  • CWRU researchers find reasons to treat gum disease early to prevent awakening HIV in dormant ...

    They discovered that byproducts of bacteria in gum disease, called metabolic small chain fatty acid (SCFA), can work together to wake up HIV in dormant T-cells and cause the virus to replicate.

  • CWRU researcher Jonathan Karn, PhD seeks way to find HIV when it is hiding.

    The research of Jonathan Karn, professor and chairman of molecular biology and microbiology, is one of four recipients of a $250,000 grant awarded earlier this year by amfAR. The national advocacy group raises money for HIV/AIDS research, education, prevention and treatment programs. Karn is heading up research on HIV latency.

Publications

  • Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis.

    Li Q, Karim AF, Ding X, Das B, Dobrowolski C, Gibson RM, Quinones-Mateu ME, Karn J, et al.

  • Mucosal Regulatory T Cells and T Helper 17 Cells in HIV-Associated Immune Activation.

    Pandiyan P, Talla A, McDonald D, Levine AD, Weinberg A, Sekaly RP, et al.

  • HIV Stigma and Social Capital in Women Living With HIV.

    Cuca YP, Asher A, Okonsky J, Kaihura A, Dawson-Rose C, Webel A.

Events

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