Alan Levine awarded grant to determine if the combination of the human immunodeficiency virus (HIV) and drug abuse is a double kick in the gut.
They discovered that byproducts of bacteria in gum disease, called metabolic small chain fatty acid (SCFA), can work together to wake up HIV in dormant T-cells and cause the virus to replicate.
The research of Jonathan Karn, professor and chairman of molecular biology and microbiology, is one of four recipients of a $250,000 grant awarded earlier this year by amfAR. The national advocacy group raises money for HIV/AIDS research, education, prevention and treatment programs. Karn is heading up research on HIV latency.
Li Q, Karim AF, Ding X, Das B, Dobrowolski C, Gibson RM, Quinones-Mateu ME, Karn J, et al.
Pandiyan P, Talla A, McDonald D, Levine AD, Weinberg A, Sekaly RP, et al.
Cuca YP, Asher A, Okonsky J, Kaihura A, Dawson-Rose C, Webel A.