Research Programs - Case Western Reserve University Department of Neurological Surgery

Tumor Neurosurgery

The Ben & Catherine Ivy Foundation (BCIF) Grant Research Collaboration Contact
The Cancer Genome Atlas (TCGA)
Chemokine Secreting Dendritic Cells for Glioma Immunotherapy
A phase II/III randomized Study of CDX-110 with Radiation and Temozolomide in Patients
Open-label, Dose Confirmation and Dosimetry Study of Interstitial 131 I-chTNT-1/BmAb (Cotara®) for the Treatment of Recurrent GBM
A prospective multi-center trial of NovoTTF-100A compared to best standard of care in patients with progressive or recurrent GBM
A Prospective First- In-Man (FIM) Safety Trial of the AutoLlTT Laser Treatment of Recurrent/Progressive Brain Tumors and involving the AutoLlTT Laser Treatment System
Phase II Study of HSPPC-96 Vaccine in Patients with Recurrent High-Grade Glioma
Protocol 020221 - A Phase II Clinical Trial Evaluating DCVax® – Brain, Autologous Dendritic Cells Pulsed with Tumor Lysate Antigen for the Treatment of Glioblastoma Multiforme
AZD2171 in Adult Patients with Neurofibromatosis Type 1
A Phase III Randomized Study of Neuradiab in Combination with External Beam Radiation and Temozolomide Versus External Beam' Radiation' and Temozolomide in Patients with Newly Diagnosed GBM
An Evaluation of Photodynamic Therapy
Strength and Resorbtion of biodegradable skull implants

Vascular Neurosurgery

Carotid Occlusion Surgery Study (COSS)
Conscious-2: A prospective, multi-center, double-blind, randomized, placebo-controlled, parallel-group study to assess the efficacy and safety of clazosentan in reducing vasospasm-related morbidity and all-cause mortality in adult patients with aneurysmal subarachnoid hemorrhage treated by surgical clipping.

Spine Neurosurgery

Activ-L Artificial Disc Clinical Study to Evaluate the Safety and Effectiveness of the Aesculap Activ-L™ Artificial Disc in the Treatment of Degenerative Disc Disease.
Engineering embronic spinal cord stem cells for spinal cord injury repair

Functional Neurosurgery